Nerve guide conduits for peripheral nerve injury repair: A review on design, materials and fabrication methods

S Vijayavenkataraman - Acta biomaterialia, 2020 - Elsevier
Peripheral nerves can sustain injuries due to loss of structure and/or function of peripheral
nerves because of accident, trauma and other causes, which leads to partial or complete …

[HTML][HTML] Polymeric guide conduits for peripheral nerve tissue engineering

H Jiang, Y Qian, C Fan, Y Ouyang - Frontiers in bioengineering and …, 2020 - frontiersin.org
Peripheral nerve injuries (PNIs) are usually caused by trauma, immune diseases, and
genetic factors. Peripheral nerve injury (PNI) may lead to limb numbness, muscle atrophy …

Repair strategies for injured peripheral nerve

C Raza, HA Riaz, R Anjum - Life sciences, 2020 - Elsevier
Compromised functional regains in about half of the patients following surgical nerve repair
pose a serious socioeconomic burden to the society. Although surgical strategies such as …

Peripheral nerve conduit: materials and structures

S Houshyar, A Bhattacharyya… - ACS chemical …, 2019 - ACS Publications
Peripheral nerve injuries (PNIs) are the most common injury types to affect the nervous
system. Restoration of nerve function after PNI is a challenging medical issue. Extended …

Regeneration of peripheral nerves by nerve guidance conduits: Influence of design, biopolymers, cells, growth factors, and physical stimuli

MD Sarker, S Naghieh, AD McInnes, DJ Schreyer… - Progress in …, 2018 - Elsevier
Injuries to the peripheral nervous system (PNS) cause neuropathies that lead to weakness
and paralysis, poor or absent sensation, unpleasant and painful neuropathies, and impaired …

Functional polymer‐based nerve guide conduits to promote peripheral nerve regeneration

X Zhang, W Qu, D Li, K Shi, R Li, Y Han… - Advanced Materials …, 2020 - Wiley Online Library
Bridging critical‐sized defects in peripheral nerves to achieve functional recovery is a
challenge for orthopedic and hand surgeons. Inadequate regeneration of peripheral nerve …

Nerve guidance conduit development for primary treatment of peripheral nerve transection injuries: A commercial perspective

BJ Parker, DI Rhodes, CM O'Brien, AE Rodda… - Acta Biomaterialia, 2021 - Elsevier
Commercial nerve guidance conduits (NGCs) for repair of peripheral nerve discontinuities
are of little use in gaps larger than 30 mm, and for smaller gaps they often fail to compete …

3D printed personalized nerve guide conduits for precision repair of peripheral nerve defects

K Liu, L Yan, R Li, Z Song, J Ding, B Liu… - Advanced …, 2022 - Wiley Online Library
The treatment of peripheral nerve defects has always been one of the most challenging
clinical practices in neurosurgery. Currently, nerve autograft is the preferred treatment …

Strategic design and fabrication of nerve guidance conduits for peripheral nerve regeneration

MD Sarker, S Naghieh, AD McInnes… - Biotechnology …, 2018 - Wiley Online Library
Nerve guidance conduits (NGCs) have been drawing considerable attention as an aid to
promote regeneration of injured axons across damaged peripheral nerves. Ideally, NGCs …

Fundamentals and current strategies for peripheral nerve repair and regeneration

CR Carvalho, RL Reis, JM Oliveira - Bioinspired Biomaterials: Advances …, 2020 - Springer
A body of evidence indicates that peripheral nerves have an extraordinary yet limited
capacity to regenerate after an injury. Peripheral nerve injuries have confounded …