[HTML][HTML] Current state and challenges of the global outcomes of dental caries research in the meta-omics era

DG Moussa, P Ahmad, TA Mansour… - Frontiers in Cellular and …, 2022 - frontiersin.org
Despite significant healthcare advances in the 21st century, the exact etiology of dental
caries remains unsolved. The past two decades have witnessed a tremendous growth in our …

[HTML][HTML] Oral microbiome and dental caries development

JS Zhang, CH Chu, OY Yu - Dentistry journal, 2022 - mdpi.com
Dental caries remains the most prevalent oral disease worldwide. The development of
dental caries is highly associated with the microbiota in the oral cavity. Microbiological …

[HTML][HTML] The evolving microbiome of dental caries

G Spatafora, Y Li, X He, A Cowan, ACR Tanner - Microorganisms, 2024 - mdpi.com
Dental caries is a significant oral and public health problem worldwide, especially in low-
income populations. The risk of dental caries increases with frequent intake of dietary …

Second era of OMICS in caries research: moving past the phase of disillusionment

MM Nascimento, E Zaura, A Mira… - Journal of dental …, 2017 - journals.sagepub.com
Novel approaches using OMICS techniques enable a collective assessment of multiple
related biological units, including genes, gene expression, proteins, and metabolites. In the …

Metabolites of the oral microbiome: important mediators of multikingdom interactions

A Barbour, O Elebyary, N Fine, M Oveisi… - FEMS Microbiology …, 2022 - academic.oup.com
The oral cavity hosts over 700 different microbial species that produce a rich reservoir of
bioactive metabolites critical to oral health maintenance. Over the last two decades, new …

Illuminating the oral microbiome and its host interactions: recent advancements in omics and bioinformatics technologies in the context of oral microbiome research

JL Baker - FEMS Microbiology Reviews, 2023 - academic.oup.com
The oral microbiota has an enormous impact on human health, with oral dysbiosis now
linked to many oral and systemic diseases. Recent advancements in sequencing, mass …

The oral microbiota: dynamic communities and host interactions

RJ Lamont, H Koo, G Hajishengallis - Nature reviews microbiology, 2018 - nature.com
The dynamic and polymicrobial oral microbiome is a direct precursor of diseases such as
dental caries and periodontitis, two of the most prevalent microbially induced disorders …

Polymicrobial interactions of oral microbiota: a historical review and current perspective

M Zhang, M Whiteley, GR Lewin - Mbio, 2022 - Am Soc Microbiol
The oral microbiota is enormously diverse, with over 700 microbial species identified across
individuals that play a vital role in the health of our mouth and our overall well-being. In …

[HTML][HTML] Functional expression of dental plaque microbiota

SN Peterson, T Meissner, AI Su, E Snesrud… - Frontiers in Cellular …, 2014 - frontiersin.org
Dental caries remains a significant public health problem and is considered pandemic
worldwide. The prediction of dental caries based on profiling of microbial species involved in …

[HTML][HTML] The human oral microbiome in health and disease: from sequences to ecosystems

JR Willis, T Gabaldón - Microorganisms, 2020 - mdpi.com
The human oral cavity is home to an abundant and diverse microbial community (ie, the oral
microbiome), whose composition and roles in health and disease have been the focus of …