Comparative performance of line probe assay and GeneXpert in the detection of rifampicin monoresistance in a TB-endemic African Country

BR Mchaki, FX Mgaya, PP Kunambi, B Hang'ombe… - Antibiotics, 2022 - mdpi.com
Rapid, accurate and reliable assays are required for timely detection of drug-resistant
tuberculosis and early initiation of second-line TB treatment as well as to minimize …

Comparison of GeneXpert and line probe assay for detection of Mycobacterium tuberculosis and rifampicin-mono resistance at the National Tuberculosis Reference …

SA Aricha, L Kingwara, NW Mwirigi, L Chaba… - BMC infectious …, 2019 - Springer
Background The dual challenge of low diagnostic sensitivity of microscopy test and technical
challenge of performing a TB culture test poses a problem for case detection and initiation of …

Comparison of rapid tests for detection of rifampicin-resistant Mycobacterium tuberculosis in Kampala, Uganda

S Ogwang, BB Asiimwe, H Traore, F Mumbowa… - BMC Infectious …, 2009 - Springer
Background Drug resistant tuberculosis (TB) is a growing concern worldwide. Rapid
detection of resistance expedites appropriate intervention to control the disease. Several …

[PDF][PDF] Non-conforming rifampicin susceptibility test reports from Xpert MTB/RIF assay: The national reference laboratory experience in Nigeria

NN Nwokoye, CC Onubogu, OP Nwadike, AT Abiodun… - probe, 2014 - researchgate.net
GeneXpert MTB/RIF assay is a technology that allows for the simultaneous detection of
Mycobacterium tuberculosis complex and rifampicin resistance in a single reaction …

Effectiveness of Xpert MTB/RIF and the line probe assay tests for the rapid detection of drug-resistant tuberculosis in the Central African Republic

A Farra, K Koula, BL Jolly, HG Gando… - PLOS Global Public …, 2023 - journals.plos.org
The Xpert MTB/RIF and Line Probe Assay (LPA) tests are more and more frequently used in
mycobacteria testing laboratories for the rapid diagnosis of multi-drug resistance (MDR-TB) …

Validation of an indigenous assay for rapid molecular detection of rifampicin resistance in presumptive multidrug-resistant pulmonary tuberculosis patients

NS Gomathi, M Singh, VP Myneedu… - Indian Journal of …, 2020 - journals.lww.com
Methods: Consecutive patients aged 18-65 yr, with symptoms suggestive of TB and with a
history of previous treatment, reporting to the National TB Elimination Programme (NTEP) …

Effects of introducing Xpert MTB/RIF test on multi-drug resistant tuberculosis diagnosis in KwaZulu-Natal South Africa

NR Dlamini-Mvelase, L Werner, R Phili, LP Cele… - BMC infectious …, 2014 - Springer
Background An algorithm instituted following Xpert MTB/RIF (Xpert) introduction in South
Africa advocates for treating all Xpert rifampicin resistant patients as MDR-TB cases while …

Diagnostic accuracy of the Xpert® MTB/XDR assay for detection of Isoniazid and second-line antituberculosis drugs resistance at central TB reference laboratory in …

T Maya, A Wilfred, C Lubinza, S Mfaume, M Mafie… - BMC Infectious …, 2024 - Springer
Introduction Early diagnosis of tuberculosis (TB) and universal access to drug-susceptibility
testing (DST) are critical elements of the WHO End TB Strategy. Current rapid tests (eg …

Evaluation of seven tests for the rapid detection of multidrug-resistant tuberculosis in Uganda

F Bwanga, ML Joloba, M Haile… - The International journal …, 2010 - ingentaconnect.com
SETTINGS: National Tuberculosis (TB) Reference Laboratory and Department of Medical
Microbiology, College of Health Sciences, Makerere University, Kampala, Uganda …

Diagnostic Accuracy of FluoroCycler® XT MTBDR Assay for Detection of Rifampicin and Isoniazid Resistant Mycobacteria tuberculosis in Clinical Isolates from Kenya

ZM Mwangi, S Ireri, H Opwaka, L Otieno, J Simam… - bioRxiv, 2023 - biorxiv.org
Abstract Background Drug-resistant TB (DR-TB) poses a major global challenge to public
health and therapeutics. It is an emerging global concern associated with increased …