Diabetic nephropathy is a progressive kidney disease resulting from long-term
hyperglycaemia in diabetic patients, and the underlying mechanism is complex and lacks …

In this study, we evaluated the nephroprotective effects of fangchinoline in rats with diabetic
nephropathy (DN). DN was induced by feeding a high-fat diet for 4 weeks and administering …

Abstract Background Water extract of Hydrangea paniculata (HP) stem, rich in coumarin
glycosides, has been demonstrated to have renal protective effect in several experimental …

Geniposide (GE) can effectively inhibit diabetic nephropathy (DN), but its mechanism is
unclear. The objective of this study was to explore the antidiabetic nephropathy effects of GE …

Background: Diabetic nephropathy (DN) is a major cause of chronic kidney disease around
the world. Endoplasmic reticulum (ER) stress plays an important role in DN progression …

Phloretin is a dihydrochalcone flavonoid from natural plants, which has protective activities
against oxidative stress and inflammation. To date, its effect on diabetic nephropathy (DN) …

Inflammation plays a central role in the development and progression of diabetic
nephropathy (DN). Researches on novel anti-inflammatory agents may offer new …

Aims Hyperglycemia leads to elevation of oxidative stress and proinflammatory cytokines
which are the main causes of diabetic nephropathy (DN). NLRP3 inflammasome and …

Nephropathy is the most prevalent microvascular disorder in diabetes mellitus. Oxidative
stress and inflammatory cascade provoked by the persistent hyperglycemic milieu play …

Abstract Swietenine (Swi), isolated from Swietenia macrophylla King ameliorates
inflammation and oxidative stress, and diabetic nephropathy has a close connection with …