The precise localization of D1 and D2 dopamine receptors within striatal neurons and
circuits is crucial information for further understanding dopamine pharmacology. We have …

We have investigated by immunohistochemistry the cellular and subcellular distribution of
the D1 dopamine receptor (DIR) in the rat striatonigral complex and its relation with the …

Potential cellular substrates for functions ascribed to the dopamine D2 receptor were
examined in rat brain using immunoperoxidase for localization of a D2 receptor peptide and …

Antibodies to the D1 dopamine receptor were used to localize this protein in several areas of
human and monkey cerebral cortex with light and electron microscopy. In addition to cell …

The pathways governing signal transduction in the mesocortical and nigrostriatal dopamine
systems of the brain are of central importance in a variety of drug actions and neurological …

Five or more dopamine receptor genes are expressed in brain. However, the
pharmacological similarities of the encoded D1-D5 receptors have hindered studies of the …

There is evidence that D 1 and D 2 dopamine receptor subtypes coexist at the cellular level
in the striatum and act synergistically to mediate the effects of dopamine. Other data suggest …

D1 dopamine receptor localization was examined by immunohistochemistry using a
polyclonal anti-peptide antibody which (i) immunoprecipitated a protein fragment encoded …

Classical antipsychotics, which block dopamine (DA) D2 receptors, show intrastriatal
variation in their effectiveness in modulating GABAergic function. To determine the cellular …

Glutamatergic neurons within the deep layers of the prefrontal cortex and dopaminergic
neurons of the substantia nigra pars compacta preferentially terminate in patch‐like regions …