Summary The interleukin‐1 (IL‐1) family of cytokines and receptors is unique in immunology
because the IL‐1 family and Toll‐like receptor (TLR) families share similar functions. More …

The signal transduction pathways activated by the proinflammatory cytokine interleukin-1 (IL-
1) have been the focus of much attention because of the important role that IL-1 plays in …

The signal transduction pathways activated by the proinflammatory cytokine interleukin-1 (IL-
1) have been the focus of much attention because of the important role that IL-1 plays in …

This issue of Seminars in Immunology on The Interleukin-1 (IL-1) Family of Ligands and
Receptors updates the rapidly expanding importance of this family. There are individual …

Interleukin-1 (IL-1) is a central mediator of the inflammatory response. It plays a role in both
systemic and local immune responses to invading microbes. There are two receptors (IL-1RI …

More than any other cytokine family, the interleukin (IL)-1 family is closely linked to the
innate immune response. This linkage became evident upon the discovery that the …

The pro-inflammatory cytokine interleukin-1 (IL-1) signals via the Type-1 IL-1 receptor (IL-
1RI), inducing an increase in the expression of many genes with roles in immunity and …

The IL-1 receptor/toll-like receptor superfamily: crucial receptors for inflammation and host
defense: Immunology Today Skip to Main Content Advertisement Trends in Immunology This …

The Toll/interleukin-1 (IL-1) receptor (TIR) family comprises two groups of transmembrane
proteins, which share functional and structural properties. The members of the IL-1 receptor …

Abstract The interleukin‐1 (IL‐1) receptor/Tolllike receptor (TLR) superfamily is a recently
defined and expanding group of receptors that participate in host responses to injury and …