Previous studies showed that exposure toVibrio vulnificus cytolysin (VVC) caused
characteristic morphologic changes and dysfunction of vascular structures in lung. VVC …

Vibrio vulnificus cytolysin (VVC) is known to be a pore-forming toxin which shows cytotoxicity
for mammalian cells in culture and induces apoptosis in endothelial cells. In order to …

Vibrio vulnificus is an estuarian bacterium that causes septicemia and serious wound
infection. The cytolysin, one of the important virulence determinants in V. vulnificus infection …

Abstract The Gram-negative bacterium Vibrio vulnificus produces hemolysin (VvhA), which
induces cytotoxicity in mammalian cells. However, our understanding of the cytotoxic …

A pathogenic bacterium, Vibrio vulnificus produces various extracellular proteases including
the elastolytic metalloprotease, VvpE. In silico analysis of its genome revealed a VvpE …

Vibrio vulnificus cytolysin forms transmembrane pores that are permeable to calcium ions in
pulmonary endothelial cells, and has been suggested as an important virulence factor that …

Vibrio vulnificus is an estuarine bacterium that causes septicemia and serious wound
infection. Cytolysin produced by V. vulnificus has been incriminated as one of the important …

Vibrio vulnificus cytolysin (VVC) has been implicated as one of the important virulence
determinants of V. vulnificus that causes serious septicemia and wound infection. An attempt …

An inflammatory response is a hallmark of necrosis evoked by bacterial pathogens. Vibrio
vulnificus, VvpE, is an elastase that is responsible for tissue necrosis and inflammation; …

Hemolyin/cytolysin (VvhA) is one of the representative exotoxins produced by Vibrio
vulnificus. Cytotoxic mechanism of VvhA has been extensively studied. However, there have …