Decreased mitochondrial electron transport proteins and increased complement mediators in plasma neural-derived exosomes of early psychosis
Potentially neurotoxic systems involved in traumatic and degenerative diseases of the brain
were assessed in acute psychosis. Astrocyte-derived exosomes (ADEs) and neuron-derived …
were assessed in acute psychosis. Astrocyte-derived exosomes (ADEs) and neuron-derived …
Neural cell‐derived plasma exosome protein abnormalities implicate mitochondrial impairment in first episodes of psychosis
Neuroprotective and other functional proteins of mitochondria were quantified in extracts of
plasma neural‐derived exosomes from ten first‐episode psychosis (FP) patients and ten …
plasma neural‐derived exosomes from ten first‐episode psychosis (FP) patients and ten …
Plasma levels of neuron-and astrocyte-derived exosomal amyloid beta1-42, amyloid beta1-40, and phosphorylated tau levels in schizophrenia patients and non …
EE Lee, C Winston-Gray, JW Barlow… - Frontiers in …, 2021 - frontiersin.org
Introduction: Cognitive deficits in people with schizophrenia (PWS) are a major predictor of
disability and functioning, yet the underlying pathophysiology remains unclear. A possible …
disability and functioning, yet the underlying pathophysiology remains unclear. A possible …
Analysis of circulating exosomes reveals a peripheral signature of astrocytic pathology in schizophrenia
M Ranganathan, M Rahman, S Ganesh… - The World Journal of …, 2022 - Taylor & Francis
Objectives Extracellular vesicles, including exosomes, cross the blood brain barrier with
their contents intact and can be assayed peripherally. Circulating exosomes have been …
their contents intact and can be assayed peripherally. Circulating exosomes have been …
[HTML][HTML] Abnormal levels of mitochondrial Ca2+ channel proteins in plasma neuron-derived extracellular vesicles of early schizophrenia
EJ Goetzl, VH Srihari, M Mustapic… - … : official publication of …, 2022 - ncbi.nlm.nih.gov
Structural alterations or quantitative abnormalities of some mitochondrial ion channels and
exchangers are associated with altered neuronal functions and increased susceptibility to …
exchangers are associated with altered neuronal functions and increased susceptibility to …
Proteomic analysis of cerebrospinal fluid extracellular vesicles reveals synaptic injury, inflammation, and stress response markers in HIV patients with cognitive …
Abstract Background Extracellular vesicles (EVs) are nano-sized particles present in most
body fluids including cerebrospinal fluid (CSF). Little is known about CSF EV proteins in …
body fluids including cerebrospinal fluid (CSF). Little is known about CSF EV proteins in …
[HTML][HTML] Complement protein levels in plasma astrocyte-derived exosomes are abnormal in conversion from mild cognitive impairment to Alzheimer's disease …
CN Winston, EJ Goetzl, JB Schwartz, FM Elahi… - Alzheimer's & Dementia …, 2019 - Elsevier
Introduction Levels of complement proteins (CPs) in plasma astrocyte-derived exosomes
(ADEs) that are abnormal in Alzheimer's disease (AD) have not been assessed in mild …
(ADEs) that are abnormal in Alzheimer's disease (AD) have not been assessed in mild …
Blood neuron-derived exosomes as biomarkers of cognitive impairment in HIV
B Sun, P Dalvi, L Abadjian, N Tang, L Pulliam - Aids, 2017 - journals.lww.com
Objective: To investigate proteins associated with neuronal damage in plasma neuron-
derived exosomes (NDE) of HIV-infected study participants as a liquid biomarker for …
derived exosomes (NDE) of HIV-infected study participants as a liquid biomarker for …
RETRACTED: increased neuroinflammatory and arachidonic acid cascade markers, and reduced synaptic proteins, in the postmortem frontal cortex from …
Schizophrenia (SZ) is a progressive, neuropsychiatric disorder associated with cognitive
impairment. A number of brain alterations have been linked to cognitive impairment …
impairment. A number of brain alterations have been linked to cognitive impairment …
Serum neuronal exosomes predict and differentiate Parkinson's disease from atypical parkinsonism
Objective Parkinson's disease is characterised neuropathologically by α-synuclein
aggregation. Currently, there is no blood test to predict the underlying pathology or …
aggregation. Currently, there is no blood test to predict the underlying pathology or …