Glucose as a potential key to fuel inflammation in rheumatoid arthritis
K Masuko - Nutrients, 2022 - mdpi.com
Glucose is the most important source of energy and homeostasis. Recent investigations are
clarifying that glucose metabolism might be altered in rheumatoid arthritis (RA), which would …
clarifying that glucose metabolism might be altered in rheumatoid arthritis (RA), which would …
Glycolysis and rheumatoid arthritis
X Chang, C Wei - International journal of rheumatic diseases, 2011 - Wiley Online Library
Glucose metabolism not only provides energy for physical activity but also mediates a
variety of physiological processes through the formation of complex signalling networks …
variety of physiological processes through the formation of complex signalling networks …
The involvement of glucose and lipid metabolism alteration in rheumatoid arthritis and its clinical implication
TT Luo, YJ Wu, Q Yin, WG Chen… - Journal of Inflammation …, 2023 - Taylor & Francis
Obviously, immune cells like T cells and macrophages play a major role in rheumatoid
arthritis (RA). On one hand, the breakdown of immune homeostasis directly induces …
arthritis (RA). On one hand, the breakdown of immune homeostasis directly induces …
[HTML][HTML] Could glucose metabolism be a sweet target for RA therapy?
S Onuora - Nature Reviews Rheumatology, 2016 - nature.com
A new study shows that glucose metabolism is altered in rheumatoid arthritis fibroblast-like
synoviocytes (RA FLS), and that inhibition of glycolysis could suppress the pathogenic …
synoviocytes (RA FLS), and that inhibition of glycolysis could suppress the pathogenic …
Critical role of glucose metabolism in rheumatoid arthritis fibroblast‐like synoviocytes
R Garcia‐Carbonell, AS Divakaruni… - Arthritis & …, 2016 - Wiley Online Library
Objective Up‐regulation of glucose metabolism has been implicated not only in tumor cell
growth but also in immune cells upon activation. However, little is known about the …
growth but also in immune cells upon activation. However, little is known about the …
Fibroblast-like synoviocytes glucose metabolism as a therapeutic target in rheumatoid arthritis
PG De Oliveira, M Farinon, E Sanchez-Lopez… - Frontiers in …, 2019 - frontiersin.org
Metabolomic studies show that rheumatoid arthritis (RA) is associated with metabolic
disruption that may be therapeutically targetable. Among them, glucose metabolism and …
disruption that may be therapeutically targetable. Among them, glucose metabolism and …
[PDF][PDF] Critical role of fibroblast-like synoviocytes glycolytic metabolism in rheumatoid arthritis
Background: Glucose metabolism up-regulation has been implicated not only in tumor cell
growth but also in immune cells on activation. However, little is known about the metabolite …
growth but also in immune cells on activation. However, little is known about the metabolite …
Increase of aerobic glycolysis mediated by activated T helper cells drives synovial fibroblasts towards an inflammatory phenotype: new targets for therapy?
P Kvacskay, N Yao, JH Schnotz, R Scarpone… - Arthritis Research & …, 2021 - Springer
Background A dysregulated glucose metabolism in synovial fibroblasts (SF) has been
associated with their aggressive phenotype in rheumatoid arthritis (RA). Even though T …
associated with their aggressive phenotype in rheumatoid arthritis (RA). Even though T …
Glycogen Metabolism and Rheumatoid Arthritis: The Role of Glycogen Synthase 1 in Regulation of Synovial Inflammation via Blocking AMP-Activated Protein Kinase …
M Shi, J Wang, Y Xiao, C Wang, Q Qiu, M Lao… - Frontiers in …, 2018 - frontiersin.org
Objective To investigate the role of glycogen metabolism in regulating rheumatoid fibroblast-
like synoviocyte (FLS)-mediated synovial inflammation and its underlying mechanism …
like synoviocyte (FLS)-mediated synovial inflammation and its underlying mechanism …
Impaired glucose metabolism underlies articular cartilage degeneration in osteoarthritis
Osteoarthritis (OA) is the leading joint disease characterized by cartilage destruction and
loss of mobility. Accumulating evidence indicates that the incidence and severity of OA …
loss of mobility. Accumulating evidence indicates that the incidence and severity of OA …
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