Chronic iEEG recordings and interictal spike rate reveal multiscale temporal modulations in seizure states

GM Schroeder, PJ Karoly, M Maturana… - arXiv preprint arXiv …, 2022 - arxiv.org
Background and Objectives: Many biological processes are modulated by rhythms on
circadian and multidien timescales. In focal epilepsy, various seizure features, such as …

Chronic intracranial EEG recordings and interictal spike rate reveal multiscale temporal modulations in seizure states

GM Schroeder, PJ Karoly, M Maturana… - Brain …, 2023 - academic.oup.com
Many biological processes are modulated by rhythms on circadian and multidien timescales.
In focal epilepsy, various seizure features, such as spread and duration, can change from …

[HTML][HTML] Resting-state background features demonstrate multidien cycles in long-term EEG device recordings

WKS Ojemann, BH Scheid, S Mouchtaris, A Lucas… - Brain Stimulation, 2023 - Elsevier
Background Longitudinal EEG recorded by implanted devices is critical for understanding
and managing epilepsy. Recent research reports patient-specific, multi-day cycles in device …

Seizure pathways and seizure durations can vary independently within individual patients with focal epilepsy

GM Schroeder, FA Chowdhury, MJ Cook… - arXiv preprint arXiv …, 2021 - arxiv.org
A seizure's electrographic dynamics are characterised by its spatiotemporal evolution, also
termed dynamical" pathway" and the time it takes to complete that pathway, which results in …

Multi-day rhythms modulate seizure risk in epilepsy

MO Baud, JK Kleen, EA Mirro, JC Andrechak… - Nature …, 2018 - nature.com
Epilepsy is defined by the seemingly random occurrence of spontaneous seizures. The
ability to anticipate seizures would enable preventative treatment strategies. A central but …

Seizure pathways change on circadian and slower timescales in individual patients with focal epilepsy

GM Schroeder, B Diehl… - Proceedings of the …, 2020 - National Acad Sciences
Personalized medicine requires that treatments adapt to not only the patient but also
changing factors within each individual. Although epilepsy is a dynamic disorder …

Evidence for long memory in focal seizure duration

JM Fan, S Chiang, VR Rao - Epilepsia Open, 2021 - Wiley Online Library
Objective A major source of disability for people with epilepsy involves uncertainty
surrounding seizure timing and severity. Although patients often report that long seizure‐free …

Cycles in epilepsy

PJ Karoly, VR Rao, NM Gregg, GA Worrell… - Nature Reviews …, 2021 - nature.com
Epilepsy is among the most dynamic disorders in neurology. A canonical view holds that
seizures, the characteristic sign of epilepsy, occur at random, but, for centuries, humans …

Fluctuations in EEG band power at subject‐specific timescales over minutes to days explain changes in seizure evolutions

M Panagiotopoulou, CA Papasavvas… - Human Brain …, 2022 - Wiley Online Library
Epilepsy is recognised as a dynamic disease, where both seizure susceptibility and seizure
characteristics themselves change over time. Specifically, we recently quantified the variable …

Slow changes in seizure pathways in individual patients with focal epilepsy

GM Schroeder, B Diehl, FA Chowdhury, JS Duncan… - BioRXiv, 2019 - biorxiv.org
Personalised medicine requires that treatments adapt to not only the patient, but changing
factors within each individual. Although epilepsy is a dynamic disorder that is characterised …