Injectable shear-thinning hydrogels for delivering osteogenic and angiogenic cells and growth factors
Bone nonunion may occur when the fracture is unstable, or blood supply is impeded. To
provide an effective treatment for the healing of nonunion defects, we introduce an injectable …
provide an effective treatment for the healing of nonunion defects, we introduce an injectable …
Injectable shear-thinning nanoengineered hydrogels for stem cell delivery
Injectable hydrogels are investigated for cell encapsulation and delivery as they can shield
cells from high shear forces. One of the approaches to obtain injectable hydrogels is to …
cells from high shear forces. One of the approaches to obtain injectable hydrogels is to …
[HTML][HTML] Regulating stem cell secretome using injectable hydrogels with in situ network formation
L Cai, RE Dewi, AB Goldstone, JE Cohen… - Advanced healthcare …, 2016 - ncbi.nlm.nih.gov
A family of Shear-thinning Hydrogels for Injectable Encapsulation and Long-term Delivery
(SHIELD) has been designed and synthesized with controlled in situ stiffening properties to …
(SHIELD) has been designed and synthesized with controlled in situ stiffening properties to …
Nanoengineered shear-thinning and bioprintable hydrogel as a versatile platform for biomedical applications
The development of bioinks based on shear-thinning and self-healing hydrogels has
recently attracted significant attention for constructing complex three-dimensional …
recently attracted significant attention for constructing complex three-dimensional …
Injectable osteogenic and angiogenic nanocomposite hydrogels for irregular bone defects
Injectable hydrogels with their 3D structure and good moldability serve as excellent
scaffolding material for regenerating irregular non load-bearing bone defects. Most of the …
scaffolding material for regenerating irregular non load-bearing bone defects. Most of the …
Synthesis of injectable shear‐thinning biomaterials of various compositions of gelatin and synthetic silicate nanoplatelet
Injectable shear‐thinning biomaterials (iSTBs) have great potential for in situ tissue
regeneration through minimally invasive therapeutics. Previously, an iSTB was developed …
regeneration through minimally invasive therapeutics. Previously, an iSTB was developed …
Angiogenesis-promoted bone repair with silicate-shelled hydrogel fiber scaffolds
K Dashnyam, JO Buitrago, T Bold… - Biomaterials …, 2019 - pubs.rsc.org
Promoting angiogenesis is a key strategy for stimulating the repair of damaged tissues,
including bone. Among other proangiogenic factors, ions have recently been considered a …
including bone. Among other proangiogenic factors, ions have recently been considered a …
Bioactive nanoengineered hydrogels for bone tissue engineering: a growth-factor-free approach
Despite bone's impressive ability to heal after traumatic injuries and fractures, a significant
need still exists for developing strategies to promote healing of nonunion defects. To …
need still exists for developing strategies to promote healing of nonunion defects. To …
Nano-silicate-reinforced and SDF-1α-loaded gelatin-methacryloyl hydrogel for bone tissue engineering
Z Shi, Y Xu, R Mulatibieke, Q Zhong, X Pan… - International journal …, 2020 - Taylor & Francis
Purpose Autologous bone grafts are the gold standard for treating bone defects. However,
limited bone supply and morbidity at the donor site restrict its extensive use. Therefore …
limited bone supply and morbidity at the donor site restrict its extensive use. Therefore …
Manufacturing functional hydrogels for inducing angiogenic–osteogenic coupled progressions in hard tissue repairs: prospects and challenges
In large bone defects, inadequate vascularization within the engineered constructs has been
a major challenge in developing clinically impactful products. It is fairly determined that bone …
a major challenge in developing clinically impactful products. It is fairly determined that bone …