CD81 as a tumor target

F Vences-Catalán, C Duault, CC Kuo… - Biochemical Society …, 2017 - portlandpress.com
CD81 participates in a variety of important cellular processes such as membrane
organization, protein trafficking, cellular fusion and cell–cell interactions. In the immune …

The tetraspanin CD81 mediates the growth and metastases of human osteosarcoma

N Mizoshiri, T Shirai, R Terauchi, S Tsuchida, Y Mori… - Cellular Oncology, 2019 - Springer
Purpose CD81 is a member of the tetraspanin family of membrane proteins. Recently, it has
been shown that CD81 may be involved in cancer cell proliferation and metastasis. As yet …

CD82 metastasis suppressor gene: a potential target for new therapeutics?

H Tonoli, JC Barrett - Trends in molecular medicine, 2005 - cell.com
The transmembrane glycoprotein CD82 is a member of the tetraspanin protein family and is
a metastasis suppressor implicated in biological processes ranging from fusion, adhesion …

CD81 is a candidate tumor suppressor gene in human gastric cancer

TH Yoo, BK Ryu, MG Lee, SG Chi - Cellular Oncology, 2013 - Springer
Background CD81 is a transmembrane protein that serves as a putative receptor for
hepatitis C virus. In addition, CD81 has been suggested to be involved in a broad range of …

CD81 regulates cell migration through its association with Rac GTPase

E Tejera, V Rocha-Perugini… - Molecular biology of …, 2013 - Am Soc Cell Biol
CD81 is a member of the tetraspanin family that has been described to have a key role in
cell migration of tumor and immune cells. To unravel the mechanisms of CD81-regulated …

Targeting the tetraspanin CD81 reduces cancer invasion and metastasis

F Vences-Catalán, R Rajapaksa… - Proceedings of the …, 2021 - National Acad Sciences
Tetraspanins are an evolutionary conserved family of proteins involved in multiple aspects of
cell physiology, including proliferation, migration and invasion, protein trafficking, and signal …

CD81 protein is expressed at high levels in normal germinal center B cells and in subtypes of human lymphomas

RF Luo, S Zhao, R Tibshirani, JH Myklebust, M Sanyal… - Human pathology, 2010 - Elsevier
CD81 is a tetraspanin cell surface protein that regulates CD19 expression in B lymphocytes
and enables hepatitis C virus infection of human cells. Immunohistologic analysis in normal …

Targeting of tetraspanin CD81 with monoclonal antibodies and small molecules to combat cancers and viral diseases

C Bailly, X Thuru - Cancers, 2023 - mdpi.com
Simple Summary Novel therapeutic targets are needed to improve treatments of aggressive
cancers and viral diseases. Tetraspanins represent an emerging class of anticancer targets …

CD151—A striking marker for cancer therapy

S Kumari, V Gayatri Devi, A Badana… - Biomarkers in …, 2015 - journals.sagepub.com
Cluster of differentiation 151 (CD151) is a member of the mammalian tetraspanin family,
which is involved in diverse functions such as maintaining normal cellular integrity, cell-to …

[HTML][HTML] CD151 in cancer progression and metastasis: a complex scenario

R Sadej, A Grudowska, L Turczyk, R Kordek… - Laboratory …, 2014 - Elsevier
Originally identified as a molecular organizer of interacting proteins into tetraspanin-
enriched microdomains, the tetraspanin CD151 has now been shown to be involved in …