Obesity and the development of type 2 diabetes: the effects of fatty tissue inflammation

DP Schuster - Diabetes, metabolic syndrome and obesity: targets …, 2010 - Taylor & Francis
Obesity is a worldwide epidemic with multiple obesity-associated health problems including
type 2 diabetes, hypertension, and cardiovascular disease. Adipose tissue serves as a fuel …

[HTML][HTML] Contribution of adipose tissue inflammation to the development of type 2 diabetes mellitus

MS Burhans, DK Hagman, JN Kuzma… - Comprehensive …, 2018 - ncbi.nlm.nih.gov
The objective of this comprehensive review is to summarize and discuss the available
evidence of how adipose tissue inflammation affects insulin sensitivity and glucose …

Adipose tissue inflammation: feeding the development of type 2 diabetes mellitus

VR Richardson, KA Smith, AM Carter - Immunobiology, 2013 - Elsevier
The global increase in obesity-induced type 2 diabetes (T2DM) represents a burden for
healthcare systems worldwide. Of particular concern is the increased morbidity associated …

Adipose tissue changes in obesity and the impact on metabolic function

S Sam, T Mazzone - Translational Research, 2014 - Elsevier
Obesity is associated with adverse alterations in adipose tissue that predispose to metabolic
dysregulation. These adverse alterations include accumulation of inflammatory …

Fatty acids and chronic low grade inflammation associated with obesity and the metabolic syndrome

AA Cooke, RM Connaughton, CL Lyons… - European journal of …, 2016 - Elsevier
The metabolic syndrome is a group of obesity associated metabolic conditions that result in
increased risk of cardiovascular disease and type 2 diabetes. Global increases in obesity …

The evolving role of inflammation in obesity and the metabolic syndrome

YH Lee, RE Pratley - Current diabetes reports, 2005 - Springer
Advances in adipose tissue biology over the past 10 years have led to an improved
understanding of the mechanisms linking obesity with the metabolic syndrome and other …

Adipose tissue inflammation: a cause or consequence of obesity-related insulin resistance?

M Blüher - Clinical science, 2016 - portlandpress.com
The worldwide obesity epidemic has become a major health concern, because it contributes
to higher mortality due to an increased risk for noncommunicable diseases including …

[HTML][HTML] Pathophysiology of obesity

D Khanna, BS Welch, A Rehman - 2021 - europepmc.org
Pathophysiology of Obesity - Abstract - Europe PMC Sign in | Create an account https://orcid.org
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Adipose tissue inflammation and ectopic lipid accumulation

T Suganami, M Tanaka, Y Ogawa - Endocrine journal, 2012 - jstage.jst.go.jp
Obesity may be viewed as a chronic low-grade inflammatory disease as well as a metabolic
disease. Indeed, unbalanced production of pro-and anti-inflammatory adipocytokines …

Impact of increased adipose tissue mass on inflammation, insulin resistance, and dyslipidemia

DA Gutierrez, MJ Puglisi, AH Hasty - Current diabetes reports, 2009 - Springer
Obesity is associated with increased prevalence of metabolic disorders, such as
inflammation, insulin resistance, and dyslipidemia, which can predispose an individual to …