Clinical translation of advanced colonic drug delivery technologies
Targeted drug delivery to the colon offers a myriad of benefits, including treatment of local
diseases, direct access to unique therapeutic targets and the potential for increasing …
diseases, direct access to unique therapeutic targets and the potential for increasing …
[HTML][HTML] Colonic drug delivery: Formulating the next generation of colon-targeted therapeutics
Colonic drug delivery can facilitate access to unique therapeutic targets and has the
potential to enhance drug bioavailability whilst reducing off-target effects. Delivering drugs to …
potential to enhance drug bioavailability whilst reducing off-target effects. Delivering drugs to …
[HTML][HTML] Strategic approaches for colon targeted drug delivery: an overview of recent advancements
SH Lee, R Bajracharya, JY Min, JW Han, BJ Park… - Pharmaceutics, 2020 - mdpi.com
Colon targeted drug delivery systems have gained a great deal of attention as potential
carriers for the local treatment of colonic diseases with reduced systemic side effects and …
carriers for the local treatment of colonic diseases with reduced systemic side effects and …
Therapeutic opportunities in colon-specific drug-delivery systems
Oral colon-specific drug-delivery systems have recently gained importance for delivering a
variety of therapeutic agents. The major obstacles to delivering drugs to the colon are the …
variety of therapeutic agents. The major obstacles to delivering drugs to the colon are the …
In Vitro Methods to Study Colon Release: State of the Art and An Outlook on New Strategies for Better In-Vitro Biorelevant Release Media
The primary focus of this review is a discussion regarding in vitro media for colon release,
but we also give a brief overview of colon delivery and the colon microbiota as a baseline for …
but we also give a brief overview of colon delivery and the colon microbiota as a baseline for …
Colon-targeted oral drug delivery systems: design trends and approaches
S Amidon, JE Brown, VS Dave - Aaps Pharmscitech, 2015 - Springer
Colon-specific drug delivery systems (CDDS) are desirable for the treatment of a range of
local diseases such as ulcerative colitis, Crohn's disease, irritable bowel syndrome, chronic …
local diseases such as ulcerative colitis, Crohn's disease, irritable bowel syndrome, chronic …
Colonic treatments and targets: issues and opportunities
EL McConnell, F Liu, AW Basit - Journal of drug targeting, 2009 - Taylor & Francis
The colon provides a plethora of therapeutic opportunities. There are multiple disease
targets, drug molecules, and colon-specific delivery systems to be explored. Clinical studies …
targets, drug molecules, and colon-specific delivery systems to be explored. Clinical studies …
Colon targeted drug delivery systems-an overview
In the last two decades colon targeted drug delivery has gained increased importance not
just for the deliver drugs for the treatment of various colonic diseases but also for its potential …
just for the deliver drugs for the treatment of various colonic diseases but also for its potential …
[HTML][HTML] Colon targeted drug delivery systems: a review on primary and novel approaches
AK Philip, B Philip - Oman medical journal, 2010 - ncbi.nlm.nih.gov
The colon is a site where both local and systemic delivery of drugs can take place. Local
delivery allows topical treatment of inflammatory bowel disease. However, treatment can be …
delivery allows topical treatment of inflammatory bowel disease. However, treatment can be …
Oral colon-specific therapeutic approaches toward treatment of inflammatory bowel disease
Introduction: Inflammatory bowel disease (IBD) is a chronic relapsing idiopathic disease. In
clinical terms, most patients require lifelong medication associated with possible unpleasant …
clinical terms, most patients require lifelong medication associated with possible unpleasant …