Low-intensity electrostimulation enhances neuroregeneration and improves erectile function in a rat model of cavernous nerve injury

M Sturny, S Karakus, R Fraga-Silva… - The journal of sexual …, 2022 - academic.oup.com
Background Neurogenic erectile dysfunction (ED) following radical prostatectomy (RP) is a
frequent complication often leading to erectile tissue remodeling and permanent ED. Low …

Electrocautery‐induced cavernous nerve injury in rats that mimics radical prostatectomy in humans

LJ Song, JQ Zhu, MK Xie, YC Wang, HB Li… - BJU …, 2014 - Wiley Online Library
Objective To investigate the early and delayed effects of cavernous nerve electrocautery
injury (CNEI) in a rat model, with the expectation that this model could be used to test …

Cavernous nerve injury using rodent animal models

O Canguven, A Burnett - The journal of sexual medicine, 2008 - academic.oup.com
Introduction With the advance of the “nerve sparing” technique in radical pelvic surgeries,
medically unaided rates of normal erectile function following surgery have improved. Precise …

A mouse model of cavernous nerve injury-induced erectile dysfunction: functional and morphological characterization of the corpus cavernosum

HR Jin, YG Chung, WJ Kim, LW Zhang… - The Journal of …, 2010 - academic.oup.com
Introduction With the advent of genetically engineered mice, it seems important to develop a
mouse model of cavernous nerve injury (CNI). Aim To establish a mouse model of CNI …

An update on the current status and future prospects of erectile dysfunction following radical prostatectomy

H Asker, D Yilmaz‐Oral, CV Oztekin, S Gur - The Prostate, 2022 - Wiley Online Library
Background Radical prostatectomy (RP) and radiation treatment are standard options for
localized prostate cancer. Even though nerve‐sparing techniques have been increasingly …

[PDF][PDF] Is it possible to recover erectile function spontaneously after cavernous nerve injury? Time-dependent structural and functional changes in corpus cavernosum …

TB Kim, MC Cho, JS Paick… - Korean Journal of …, 2012 - synapse.koreamed.org
Purpose: There has been a scarcity of integrated, long-term (> 4 week) studies on structural
and functional alterations in the penis according to the period following cavernous nerve …

Restoring erectile function by combined treatment with JNK inhibitor and HDAC inhibitor in a rat model of cavernous nerve injury

J Lee, MC Cho, H Son, SW Kim - Andrology, 2022 - Wiley Online Library
Background The main pathophysiologic conditions of erectile dysfunction (ED) after radical
prostatectomy are considered to be corporal fibrosis and apoptosis induced by cavernosal …

Effect of a local delivery of triiodothyronine (T3) within neuroregenerative guide on recovery of erectile function in a rat-model of cavernous nerve injury

T Bessede, B Alsaid, L Ferretti, M Pierre… - The journal of sexual …, 2010 - academic.oup.com
Introduction A promoting effect of thyroid hormones has been established on the maturation
of central and peripheral nervous systems. However, effects on autonomic nerves have …

Spontaneous regeneration of nerve Fiber and irreversibility of corporal smooth muscle fibrosis after cavernous nerve crush injury: evidence from serial transmission …

YN Wu, KC Chen, CH Liao, HS Chiang - Urology, 2018 - Elsevier
Objective To determine the pathophysiological progresses following bilateral cavernous
nerve crushing injury, as an index for a treatment point and establishment of adequate …

The effect of vascular endothelial growth factor and brain‐derived neurotrophic factor on cavernosal nerve regeneration in a nerve‐crush rat model

PS Hsieh, DJ Bochinski, GT Lin, L Nunes… - BJU …, 2003 - Wiley Online Library
OBJECTIVE To test the hypothesis that an intracavernosal injection with brain‐derived
neurotrophin factor (BDNF) and vascular endothelial growth factor (VEGF) can facilitate …