[HTML][HTML] Impact of prenatal cold stress on placental physiology, inflammatory response, and apoptosis in rats

S Lian, J Guo, L Wang, W Li, J Wang, H Ji, F Kong… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Prenatal cold stress is one of the earliest factors affecting mammalian health, and is
associated with neonatal growth retardation and immune dysfunction, thus increasing …

Effects of prenatal cold stress on maternal serum metabolomics in rats

S Lian, W Li, D Wang, B Xu, X Guo, H Yang, J Wang - Life sciences, 2020 - Elsevier
Our previous studies have shown that prenatal cold stress leads to placental inflammatory
response and induces anxiety-like behavior reduced in offspring rats. However, the role and …

[HTML][HTML] Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse

H Guo, Y Yang, Y Qiao, J He, W Yao… - … and Environmental Safety, 2021 - Elsevier
High ambient temperature-induced heat stress (HS) during pregnancy may affect the
placental function and fetal development. Late gestation is a critical period of the developing …

Response of the maternal hypothalamus to cold stress during late pregnancy in rats

D Wang, B Xu, J Wang, H Wang, J Guo, H Ji, S Li… - Brain Research, 2019 - Elsevier
Maternal stress is a key risk factor in the development of offspring. We previously identified
prenatal cold stress-induced anxiety-like behavior reduced in the offspring of rats along with …

Ambient temperature, heat stress and fetal growth: a review of placenta-mediated mechanisms

W Cowell, N Ard, T Herrera, EA Medley… - Molecular and Cellular …, 2023 - Elsevier
Pregnancy is increasingly considered a period of vulnerability for extreme heat exposure.
Multiple lines of evidence support that heat stress is associated with placental insufficiency …

Prenatal cold stress: Effect on maternal hippocampus and offspring behavior in rats

S Lian, D Wang, B Xu, W Guo, L Wang, W Li… - Behavioural Brain …, 2018 - Elsevier
In mammals, environmental factors including cold stress exert dramatic effects on adult
health during late gestation, the cold stress response refers to an organism's response to …

Whole transcriptome analysis of trophoblasts under hypoxia

J Sun, B Song, Y Ban, C Ma, J Sun, D Ai, Z Nan… - Placenta, 2022 - Elsevier
Introduction A physiological hypoxia environment exists at maternal-fetal interface during
early pregnancy. In addition, there is a pathological hypoxic microenvironment in patients …

Maternal, placental, and fetal responses to intermittent heat exposure during late gestation in mice

K Olivier, LA Reinders, MW Clarke, RC Crew… - Reproductive …, 2021 - Springer
Physiological adaptations during heat exposure are critical in pregnancy. Maternal
thermoregulation has to accommodate the increased metabolic load of the developing fetus …

[HTML][HTML] Sleep deprivation during pregnancy leads to poor fetal outcomes in Sprague–Dawley rats

J Li, X Peng, H Zhong, S Liu, J Shi, X Zhou… - Journal of Reproductive …, 2023 - Elsevier
Sleep deprivation is a common problem during pregnancy, but its impact on the fetus
remains unclear. We aimed to investigate the effect of sleep deprivation during pregnancy …

[HTML][HTML] Ovarian PERK/NRF2/CX43/StAR/progesterone pathway activation mediates female reproductive dysfunction induced by cold exposure

M Ding, Y Lu, Q Wen, C Xing, X Huang, Y Zhang… - Scientific Reports, 2024 - nature.com
Ambient air temperature is a key factor affecting human health. Female reproductive
disorders are representative health risk events under low temperature. However, the …