HPA axis responses to psychological challenge linking stress and disease: What do we know on sources of intra-and interindividual variability?

S Zänkert, S Bellingrath, S Wüst, BM Kudielka - Psychoneuroendocrinology, 2019 - Elsevier
Stress is an ubiquitous phenomenon with significant impact on human physiology when it
lasts too long, when it is too intense, or when it hits vulnerable individuals. Examining the …

Human models in acute and chronic stress: assessing determinants of individual hypothalamus–pituitary–adrenal axis activity and reactivity

BM Kudielka, S Wüst - Stress, 2010 - Taylor & Francis
Stress is one of the most significant health problems in modern societies and the 21st
century. This explains a pressing need for investigations into the biological pathways linking …

Covariance between psychological and endocrine responses to pharmacological challenge and psychosocial stress: a question of timing

W Schlotz, R Kumsta, I Layes, S Entringer… - Psychosomatic …, 2008 - journals.lww.com
Objective: To test if the covariance of hypothalamus-pituitary-adrenal (HPA) axis and
subjective-psychological responses to stress is dependent on different dynamics of these …

Factors promoting vulnerability to dysregulated stress reactivity and stress‐related disease

AL Russell, JG Tasker, AB Lucion… - Journal of …, 2018 - Wiley Online Library
Effective coordination of the biological stress response is integral for the behavioural well‐
being of an organism. Stress reactivity is coordinated by an interplay of the neuroendocrine …

The effects of sex and hormonal status on the physiological response to acute psychosocial stress

E Kajantie, DIW Phillips - Psychoneuroendocrinology, 2006 - Elsevier
Whether one is male or female is one of the most important determinants of human health.
While males are more susceptible to cardiovascular and infectious disease, they are …

Hypothalamic–pituitary–adrenal and hypothalamic–pituitary–gonadal axes: sex differences in regulation of stress responsivity

MG Oyola, RJ Handa - stress, 2017 - Taylor & Francis
Gonadal hormones play a key role in the establishment, activation, and regulation of the
hypothalamic–pituitary–adrenal (HPA) axis. By influencing the response and sensitivity to …

Modulation of the hypothalamic-pituitary-adrenal axis by early life stress exposure

M Van Bodegom, JR Homberg… - Frontiers in cellular …, 2017 - frontiersin.org
Exposure to stress during critical periods in development can have severe long-term
consequences, increasing overall risk on psychopathology. One of the key stress response …

HPA-axis and inflammatory reactivity to acute stress is related with basal HPA-axis activity

X Chen, D Gianferante, L Hanlin, A Fiksdal… - …, 2017 - Elsevier
Introduction Inflammation is drawing attention as pathway between psychosocial stress and
health, and basal HPA axis activity has been suggested to exert a consistent regulatory …

Human hypothalamus–pituitary–adrenal axis responses to acute psychosocial stress in laboratory settings

P Foley, C Kirschbaum - Neuroscience & Biobehavioral Reviews, 2010 - Elsevier
Cumulative acute psychosocial stress is thought to promote the development of a range of
disorders which suggests that biomarkers for the physiological response may become …

Habituation of cortisol responses to repeated psychosocial stress—further characterization and impact of genetic factors

S Wüst, IS Federenko, EFC van Rossum… - …, 2005 - Elsevier
Although a rapid response habituation to repeated stress exposure is a key characteristic of
the hypothalamus–pituitary–adrenal (HPA) axis, several studies document a substantial …