Mast Cell Infiltration in Liver of Cannabigerol Treated Methionine/Choline Deficient Diet Induced Mice Non-Alcoholic Steatohepatitis Model

A Jacobsen - 2021 - digscholarship.unco.edu
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease across
the world. Once it progresses to non-alcoholic steatohepatitis (NASH), little can be done to …

Investigating the Therapeutic Potential of Cannabigerol (CBG) in Female Nonalcoholic Steatohepatitis (Nash) Mouse Model

RA Joly - 2023 - digscholarship.unco.edu
Nonalcoholic Steatohepatitis (NASH) is a progressive form of nonalcoholic fatty liver disease
(NAFLD) characterized by inflammation, fibrosis, steatosis, and oxidative stress, in addition …

[HTML][HTML] Low-dose administration of cannabigerol attenuates inflammation and fibrosis associated with methionine/choline deficient diet-induced NASH model via …

N Aljobaily, K Krutsinger, MJ Viereckl, R Joly… - Nutrients, 2022 - mdpi.com
Non-Alcoholic Steatohepatitis (NASH) is the progressive form of Non-Alcoholic Fatty Liver
Disease (NAFLD). NASH is distinguished by severe hepatic fibrosis and inflammation. The …

Mast cells promote nonalcoholic fatty liver disease phenotypes and microvesicular steatosis in mice fed a western diet

L Kennedy, V Meadows, A Sybenga, J Demieville… - …, 2021 - Wiley Online Library
Background and Aims Nonalcoholic fatty liver disease (NAFLD) is simple steatosis but can
develop into nonalcoholic steatohepatitis (NASH), characterized by liver inflammation …

Cigarette smoking differentially regulates inflammatory responses in a mouse model of nonalcoholic steatohepatitis depending on exposure time point

JW Kim, Z Zhou, H Yun, S Park, SJ Choi, SH Lee… - Food and Chemical …, 2020 - Elsevier
Cigarette smoke (CS) is a risk factor for the development of nonalcoholic fatty liver disease.
However, the role of mainstream CS (MSCS) in the pathogenesis of nonalcoholic …

[HTML][HTML] Dynamics of liver macrophage subsets in a novel mouse model of non-alcoholic steatohepatitis using C57BL/6 Mice

N Makiuchi, S Takano, Y Tada, K Kasai, N Igarashi… - Biomedicines, 2023 - mdpi.com
Macrophages are critical for the development of non-alcoholic steatohepatitis (NASH). Our
previous findings in TSNO mouse livers showed that an iHFC (high-fat/cholesterol/cholate) …

[HTML][HTML] Methionine-and choline-deficient diet–induced nonalcoholic steatohepatitis is associated with increased intestinal inflammation

DR Matthews, H Li, J Zhou, Q Li, S Glaser… - The American Journal of …, 2021 - Elsevier
Inflammation drives the pathogenesis of nonalcoholic steatohepatitis (NASH). The current
study examined changes in intestinal inflammation during NASH. In male C57BL/6J mice …

[HTML][HTML] Metformin prevents and reverses inflammation in a non-diabetic mouse model of nonalcoholic steatohepatitis

Y Kita, T Takamura, H Misu, T Ota, S Kurita… - 2012 - journals.plos.org
Background Optimal treatment for nonalcoholic steatohepatitis (NASH) has not yet been
established, particularly for individuals without diabetes. We examined the effects of …

A combination of geniposide and chlorogenic acid combination ameliorates nonalcoholic steatohepatitis in mice by inhibiting Kupffer cell activation

X Xin, Y Jin, X Wang, B Cai, Z An… - BioMed research …, 2021 - Wiley Online Library
The incidence of nonalcoholic steatohepatitis (NASH) is increasing worldwide. Activation of
Kupffer cells (KCs) is central to the development of diet‐induced NASH. We investigated …

[HTML][HTML] Morphological and functional characterization of non-alcoholic fatty liver disease induced by a methionine-choline-deficient diet in C57BL/6 mice

H Itagaki, K Shimizu, S Morikawa… - International journal of …, 2013 - ncbi.nlm.nih.gov
Background: Non-alcoholic fatty liver disease (NAFLD), including non-alcoholic
steatohepatitis (NASH), appears to be increasingly common worldwide. Its histopathology …