There has been a growing body of studies on benzothiazoles and benzothiazole derivatives
as strong and effective anti-tumor agents against lung, liver, pancreas, breast, and brain …

Benzothiazoles are a class of heterocycles with multiple applications as anticancer,
antibiotic, antiviral, and anti‐inflammatory agents. Benzothiazole is a privileged scaffold in …

A hypoxic environment occurs predominantly in tumors. During the growth phase of a tumor,
it grows until it exceeds its blood supply, leaving regions of the tumor in which the oxygen …

Benzothiazole is an organic compound bearing a heterocyclic nucleus (thiazole) which
imparts a broad spectrum of biological activities to it. The significant and potent activity of …

Cancer is one of the major causes of mortality and morbidity worldwide. Substantial
research efforts have been made to develop new chemical entities with improved anticancer …

Heterocyclic compounds, analogs and derivatives have attracted attention due to their
diverse biological and pharmacological properties. Benzoheterocycles such as …

In efforts to develop a new class of anticancer agents with improved efficacy and selective
action, a series of N-alkylbromo-benzothiazoles were synthesized and evaluated for in vitro …

Tumor microenvironment is a complex multistep event which involves several hallmarks that
transform the normal cell into cancerous cell. Designing the novel antagonistic molecule to …

Abstract According to World Health Organization Cancer is the second leading cause of
death worldwide which accounted for an estimated 10.0 million deaths in 2020. Globally, the …

Over the past few decades, significant advancements in the discovery of anticancer
medicines have yielded various novel agents, both synthetic and natural in origin. Thiazoles …