Although oral drug delivery is the preferred administration route and has been used for
centuries, modern drug discovery and development pipelines challenge conventional …

Most of the drugs that are available in the marketplace are administered via the oral route,
which is a convenient and cost effective route of administration (Lipinski 1995; Lipinski 2000; …

To be effective, drugs in an oral dosage form first must be absorbed and then reach the
target organs via systemic circulation. Barriers that prevent drugs from reaching the systemic …

Background Lifestyle issues contribute to the development of obesity, type 2 diabetes, and
cardiovascular disease. Together with appropriate diet and exercise, nutraceuticals may …

The absorption of oral drugs is frequently plagued by significant variability with potentially
serious therapeutic consequences. The source of variability can be traced back to …

Oral drug absorption is a process influenced by the physicochemical and biopharmaceutical
properties of the drug and its inter-relationship with the gastrointestinal tract. Drug solubility …

The purpose of this study was to increase the understanding of in vivo colonic drug
absorption in humans by summarizing and evaluating all regional in vivo human absorption …

The release and absorption profile of an oral medication is influenced by the
physicochemical properties of the drug and its formulation, as well as by the anatomy and …

The oral route is the most common and practical means of drug administration, particularly
from a patient's perspective. However, the pharmacokinetic profile of oral drugs depends on …

Oral administration is the most commonly used route for drug delivery owing to its cost-
effectiveness, ease of administration, and high patient compliance. However, the absorption …