Characterization and therapeutic use of extracellular vesicles derived from platelets

T Spakova, J Janockova, J Rosocha - International Journal of Molecular …, 2021 - mdpi.com
Autologous blood products, such as platelet-rich plasma (PRP), are gaining increasing
interest in different fields of regenerative medicine. Although growth factors, the main …

Isolation of platelet-derived exosomes from human platelet-rich plasma: biochemical and morphological characterization

M Saumell-Esnaola, D Delgado… - International Journal of …, 2022 - mdpi.com
Platelet-Rich Plasma (PRP) is enriched in molecular messengers with restorative effects on
altered tissue environments. Upon activation, platelets release a plethora of growth factors …

[HTML][HTML] Platelet-derived extracellular vesicles: an emerging therapeutic approach

SC Tao, SC Guo, CQ Zhang - International journal of biological …, 2017 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are a newly-discovered way by which cells communicate with
their neighbors, as well as transporting cargos which once were considered to be limited by …

[PDF][PDF] Exosomes: novel effectors of human platelet lysate activity

E Torreggiani, F Perut, L Roncuzzi, N Zini, SR Baglìo… - Eur Cell Mater, 2014 - exosmart.co
Despite the popularity of platelet-rich plasma (PRP) and platelet lysate (PL) in orthopaedic
practice, the mechanism of action and the effectiveness of these therapeutic tools are still …

Prospective therapeutic applications of platelet extracellular vesicles

J Johnson, YW Wu, C Blyth, G Lichtfuss… - Trends in …, 2021 - cell.com
There is much interest in the use of extracellular vesicles (EVs) as a subcellular therapy for
regenerative medicine and drug delivery. Blood-borne platelets represent a source of …

Platelet-derived extracellular vesicles for regenerative medicine

M Antich-Rosselló, MA Forteza-Genestra… - International journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) present a great potential for the development of new treatments
in the biomedical field. To be used as therapeutics, many different sources have been used …

Platelet‐rich plasma‐derived extracellular vesicles: A superior alternative in regenerative medicine?

J Wu, Y Piao, Q Liu, X Yang - Cell Proliferation, 2021 - Wiley Online Library
Abstract Platelet‐rich plasma (PRP), due to its promising therapeutic properties, has been
used in regenerative medicine for more than 30 years and numerous encouraging outcomes …

Shedding light on the cell biology of platelet-derived extracellular vesicles and their biomedical applications

PK Chaudhary, S Kim, S Kim - Life, 2023 - mdpi.com
EVs are membranous subcellular structures originating from various cells, including
platelets which consist of biomolecules that can modify the target cell's pathophysiological …

Advances in platelet rich plasma-derived extracellular vesicles for regenerative medicine: A systematic-narrative review

E Anitua, M Troya, JM Falcon-Pérez… - International Journal of …, 2023 - mdpi.com
The use of platelet-rich plasma (PRP) has gained increasing interest in recent decades. The
platelet secretome contains a multitude of growth factors, cytokines, chemokines, and other …

Isolation and characterization of platelet-derived extracellular vesicles

MT Aatonen, T Öhman, TA Nyman… - Journal of …, 2014 - Taylor & Francis
Background Platelet-derived extracellular vesicles (EVs) participate, for example, in
haemostasis, immunity and development. Most studies of platelet EVs have targeted …