Rates of obesity and diabetes have increased significantly over the past decades and the
prevalence is expected to continue to rise further in the coming years. Many observations …

Obesity and type 2 diabetes have both been associated with increased cancer risk and are
becoming increasingly prevalent. Metabolic abnormalities such as insulin resistance and …

Abstract Purpose of Review Adipocytes have adapted to store energy in the form of lipid and
also secrete circulating factors called adipokines that signal to other tissues to coordinate …

Obesity and type 2 diabetes are becoming increasingly prevalent worldwide, and both are
associated with an increased incidence and mortality from many cancers. The metabolic …

Obesity and its associated metabolic dysregulation are established risk factors for many
cancers. However, the biologic mechanisms underlying this relationship remain …

The increasing incidence of obesity and its co-morbid conditions poses a great challenge to
global health. In addition to cardiovascular disease and diabetes, epidemiological data …

Historically, cancer research has focused on identifying mutations or amplification of genes
within the tumor, which informed the development of targeted therapies against affected …

The incidence of obesity in US adults has been steadily increasing over the past few
decades. Many comorbidities associated with obesity have been well-established such as …

Obesity and type 2 diabetes (T2D) increase the prevalence and worsen the prognosis of
more than a dozen tumor types; however, the mechanism for this association remains hotly …

Obesity leads to many diseases including hypercholesterolemia, type-2 diabetes,
hypertension, cardiovascular disease, and cancer. It is the fastest-growing lethal disease in …