The role of N6-methyladenosine methylation in PAHs-induced cancers

Y Wei, X Guo, L Li, W Xue, L Wang, C Chen… - … Science and Pollution …, 2023 - Springer
Polycyclic aromatic hydrocarbons (PAHs), which are a wide range of environmental
toxicants, may act on humans through inhalation, ingestion, and skin contact, resulting in a …

The role of N6-methyladenosine methylation in environmental exposure-induced health damage

Y Feng, T Liu, S Xu, Y Ren, Y Ge, L Yin, Y Pu… - … Science and Pollution …, 2022 - Springer
The health risks caused by environmental pollution have long been of substantial concern.
With the development of epigenetics, a large number of studies have demonstrated that N6 …

[HTML][HTML] Effects and mechanisms of N6-methyladenosine RNA methylation in environmental pollutant-induced carcinogenesis

T Li, Z Xu, K Zhang, X Yang, A Thakur, S Zeng… - Ecotoxicology and …, 2024 - Elsevier
Environmental pollution, including air pollution, plastic contamination, and heavy metal
exposure, is a pressing global issue. This crisis contributes significantly to pollution-related …

Interaction between N6-methyladenosine (m6A) modification and environmental chemical-induced diseases in various organ systems

X Zhu, H Fu, J Sun, Q Xu - Chemico-Biological Interactions, 2023 - Elsevier
A wide variety of chemicals are ubiquitous in the environment and thus exposure to these
environmental chemicals poses a serious threat to public health. Particularly, environmental …

Novel insights into the roles of RNA N6-methyladenosine modification in regulating gene expression during environmental exposures

D Li, X Zhu, Y Li, X Zeng - Chemosphere, 2020 - Elsevier
Abstract N 6-methyladenosine (m 6 A) is one of the most common RNA modifications in
eukaryotes involved in the regulation of post-transcriptional gene expression, as well as the …

N6-methyladenosine mediates arsenite-induced human keratinocyte transformation by suppressing p53 activation

T Zhao, D Sun, M Zhao, Y Lai, Y Liu, Z Zhang - Environmental Pollution, 2020 - Elsevier
Abstract N 6-methyladenosine (m 6 A), the most abundant and reversible RNA modification,
plays critical a role in tumorigenesis. However, whether m 6 A can regulate p53, a leading …

N6-methyladenosine mediates the cellular proliferation and apoptosis via microRNAs in arsenite-transformed cells

S Gu, D Sun, H Dai, Z Zhang - Toxicology letters, 2018 - Elsevier
Abstract N 6-methyladenosine (m 6 A) modification is implicated to play an important role in
cellular biological processes, but its regulatory mechanisms in arsenite-induced …

N6-methyladenosine plays a dual role in arsenic carcinogenesis by temporal-specific control of core target AKT1

T Zhao, D Sun, W Xiong, J Man, Q Zhang… - Journal of Hazardous …, 2023 - Elsevier
High-profile RNA epigenetic modification N 6-methyladenosine (m 6 A), as a double-edged
sword for cancer, can either promote or inhibit arsenic-induced skin carcinogenesis …

Oxidative stress: One potential factor for arsenite-induced increase of N6-methyladenosine in human keratinocytes

T Zhao, X Li, D Sun, Z Zhang - Environmental Toxicology and …, 2019 - Elsevier
Abstract N 6-methyladenosine (m 6 A) modification is affected by oxidative stress and gets
involved in arsenite toxicity. However, whether oxidative stress is one factor in arsenite …

The emerging role of N6-methyladenine RNA methylation in metal ion metabolism and metal-induced carcinogenesis

Y Liang, H Wang, B Wu, N Peng, D Yu, X Wu… - Environmental …, 2023 - Elsevier
Abstract N 6-methyladenine (m 6 A) is the most common and abundant internal modification
in eukaryotic mRNAs, which can regulate gene expression and perform important biological …