Reducing harm associated with anticoagulation: practical considerations of argatroban therapy in heparin-induced thrombocytopenia

MJ Hursting, J Soffer - Drug safety, 2009 - Springer
Argatroban is a hepatically metabolized, direct thrombin inhibitor used for prophylaxis or
treatment of thrombosis in heparin-induced thrombocytopenia (HIT) and for patients with or …

Update on argatroban for the prophylaxis and treatment of heparin-induced thrombocytopenia type II

E Grouzi - Journal of Blood Medicine, 2014 - Taylor & Francis
Heparin-induced thrombocytopenia (HIT) is a rare but potentially severe complication of
heparin therapy that is strongly associated with venous and arterial thrombosis (HIT and …

Transitioning from argatroban to warfarin therapy in patients with heparin-induced thrombocytopenia

MJ Hursting, BE Lewis… - Clinical and applied …, 2005 - journals.sagepub.com
Argatroban, a direct thrombin inhibitor used for thromboprophylaxis or treatment in heparin-
induced thrombocytopenia (HIT), is routinely monitored using the activated partial …

Weight-based argatroban dosing nomogram for treatment of heparin-induced thrombocytopenia

AJ Ansara, S Arif, RD Warhurst - Annals of …, 2009 - journals.sagepub.com
BACKGROUND Manufacturer recommendations for argatroban use in the setting of heparin-
induced thrombocytopenia (HIT) state that the dosage should be titrated to a goal activated …

Argatroban: a review of its use in the management of heparin-induced thrombocytopenia

S Dhillon - American journal of cardiovascular drugs, 2009 - Springer
Argatroban, a highly selective direct thrombin inhibitor, is indicated for use as an
anticoagulant for the treatment and prophylaxis of thrombosis in patients with heparin …

[HTML][HTML] Managing argatroban in heparin‐induced thrombocytopenia: a retrospective analysis of 729 treatment days in 32 patients with confirmed heparin‐induced …

M Marchetti, S Barelli, T Gleich, FJ Gomez… - British Journal of …, 2022 - ncbi.nlm.nih.gov
Argatroban is a first‐line anticoagulant for patients with heparin‐induced thrombocytopenia
(HIT). Published data on practical aspects of its use in HIT are lacking. We aim to establish …

Argatroban anticoagulation in patients with heparin-induced thrombocytopenia requiring renal replacement therapy

BV Reddy, EJ Grossman, SA Trevino… - Annals of …, 2005 - journals.sagepub.com
BACKGROUND: Argatroban, a direct thrombin inhibitor, is used for prophylaxis or treatment
of thrombosis in heparin-induced thrombocytopenia (HIT). The recommended initial dose is …

Argatroban therapy in heparin-induced thrombocytopenia

L Rice, M Beiderlinden, MJ Hursting - Heparin-induced …, 2012 - taylorfrancis.com
When heparin-induced thrombocytopenia (HIT) is reasonably suspected, all heparin
exposures should be eliminated and an alternative nonheparin anticoagulant expeditiously …

Transitioning from argatroban to warfarin in heparin-induced thrombocytopenia: an analysis of outcomes in patients with elevated international normalized ratio (INR)

JR Bartholomew, MJ Hursting - Journal of thrombosis and thrombolysis, 2005 - Springer
Background: Heparin-induced thrombocytopenia (HIT) can lead to catastrophic
thromboembolic complications and requires treatment with an alternative, rapidly active …

Effect of renal function on argatroban therapy in heparin-induced thrombocytopenia

LM Guzzi, DA McCollum, MJ Hursting - Journal of thrombosis and …, 2006 - Springer
Background Argatroban is considered to be an alternative anticoagulant of choice in
patients with heparin-induced thrombocytopenia (HIT) and renal impairment. The …