Mass production and use of antibiotics and antimicrobials in medicine and agriculture have
existed for over 60 years, and has substantially benefited public health and agricultural …

The vast majority of antibiotic resistant genes (ARG) acquired by human pathogens have
originated from the natural environment. Therefore, understanding factors that influence …

Debate exists about whether agricultural versus medical antibiotic use drives increasing
antibiotic resistance (AR) across nature. Both sectors have been inconsistent at antibiotic …

Manure can be a source of antibiotic resistance genes (ARGs) that enter the soil. However,
previous studies assessing ARG persistence in soil have generally lacked continuity over …

Highlights•Which drugs, bacteria and genes should be measured in agroecosystems?•
Defining baseline levels of drugs, bacteria and genes.•Connecting agriculture and clinic …

Antibiotic resistance genes (ARGs), environmental pollutants of emerging concern, have
posed a potential threat to the public health. Soil is one of the huge reservoirs and …

Antibiotic resistance is a global phenomenon with severe epidemiological ramifications.
Although the spread of antibiotic resistance is generally associated with selection derived …

Antibiotic resistance genes are typically isolated by cloning from cultured bacteria or by
polymerase chain reaction (PCR) amplification from environmental samples. These methods …

Soil is an important environmental reservoir of antibiotic resistance genes (ARGs), which are
increasingly recognized as environmental contaminants. Methods to assess the risks …

Animal manure fertilization facilitates the proliferation and dissemination of antibiotic
resistance genes (ARGs) in soil, posing high risks to humans and ecosystem health …