The Pitx2: miR-200c/141: noggin pathway regulates Bmp signaling and ameloblast differentiation

H Cao, A Jheon, X Li, Z Sun, J Wang, S Florez… - …, 2013 - journals.biologists.com
The mouse incisor is a remarkable tooth that grows throughout the animal's lifetime. This
continuous renewal is fueled by adult epithelial stem cells that give rise to ameloblasts …

Failure of Tooth Formation Mediated by miR-135a Overexpression via BMP Signaling

EJ Kim, MJ Lee, L Li, KS Yoon… - Journal of Dental …, 2014 - journals.sagepub.com
MicroRNAs (miRNAs) are known to regulate a variety of gene functions in many tissues and
organs, but their expression and function in tooth development are not well-understood. A …

[HTML][HTML] A pituitary homeobox 2 (Pitx2): microRNA-200a-3p: β-catenin pathway converts mesenchymal cells to amelogenin-expressing dental epithelial cells

T Sharp, J Wang, X Li, H Cao, S Gao, M Moreno… - Journal of Biological …, 2014 - ASBMB
Pitx2, Wnt/β-catenin signaling, and microRNAs (miRs) play a critical role in the regulation of
dental stem cells during embryonic development. In this report, we have identified a Pitx2: β …

[HTML][HTML] microRNA miR-34a regulates cytodifferentiation and targets multi-signaling pathways in human dental papilla cells

M Wan, B Gao, F Sun, Y Tang, L Ye, Y Fan, OD Klein… - PloS one, 2012 - journals.plos.org
Odontogenesis relies on the reciprocal signaling interactions between dental epithelium and
neural crest-derived mesenchyme, which is regulated by several signaling pathways. Subtle …

MiR-361-3p/Nfat5 Signaling Axis Controls Cementoblast Differentiation

HQ Liao, H Liu, HL Sun, JB Xiang… - Journal of dental …, 2019 - journals.sagepub.com
The development of periodontal tissue is a complex process, including cementoblast
proliferation and differentiation. Emerging reports suggest that microRNAs (miRNAs) play …

MicroRNA control of tooth formation and eruption

Y Jin, C Wang, S Cheng, Z Zhao, J Li - Archives of Oral Biology, 2017 - Elsevier
Tooth development involves epithelium invagination, mesenchyme aggregation, and
epithelium–mesenchyme communication. A sophisticated signaling pathway network …

[HTML][HTML] miR-145 and miR-143 regulate odontoblast differentiation through targeting Klf4 and Osx genes in a feedback loop

H Liu, H Lin, L Zhang, Q Sun, G Yuan, L Zhang… - Journal of Biological …, 2013 - ASBMB
Dentin tissue is derived from mesenchymal cells induced into the odontoblast lineage. The
differentiation of odontoblasts is a complex process regulated by several transcriptional …

Retracted: The Role of MicroRNA‐143‐5p in the Differentiation of Dental Pulp Stem Cells into Odontoblasts by Targeting Runx2 via the OPG/RANKL Signaling …

FL Zhan, XY Liu, XB Wang - 2018 - Wiley Online Library
This study aims to elucidate the mechanisms by which microRNA‐143‐5p (miR‐143‐5p)
targets runt‐related transcription factor 2 (Runx2) in the differentiation of dental pulp stem …

[HTML][HTML] microRNA-875-5p plays critical role for mesenchymal condensation in epithelial-mesenchymal interaction during tooth development

K Funada, K Yoshizaki, K MIyazaki, X Han, T Yuta… - Scientific reports, 2020 - nature.com
Epithelial-mesenchymal interaction has critical roles for organ development including teeth,
during which epithelial thickening and mesenchymal condensation are initiated by precise …

[HTML][HTML] Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs

F Michon, M Tummers, M Kyyrönen, MJ Frilander… - Developmental …, 2010 - Elsevier
Teeth form as appendages of the ectoderm and their morphogenesis is regulated by tissue
interactions mediated by networks of conserved signal pathways. Micro-RNA (miRNA) …