[HTML][HTML] In vitro functional analysis of gRNA sites regulating assembly of hepatitis B virus
The roles of RNA sequence/structure motifs, Packaging Signals (PSs), for regulating
assembly of an HBV genome transcript have been investigated in an efficient in vitro assay …
assembly of an HBV genome transcript have been investigated in an efficient in vitro assay …
[HTML][HTML] Dysregulation of hepatitis B virus nucleocapsid assembly in vitro by RNA-binding small ligands
N Patel, F Abulwerdi, F Fatehi, IW Manfield… - Journal of molecular …, 2022 - Elsevier
RNA sequences/motifs dispersed across the genome of Hepatitis B Virus regulate formation
of nucleocapsid-like particles (NCPs) by core protein (Cp) in vitro, in an epsilon/polymerase …
of nucleocapsid-like particles (NCPs) by core protein (Cp) in vitro, in an epsilon/polymerase …
Cell-free hepatitis B virus capsid assembly dependent on the core protein C-terminal domain and regulated by phosphorylation
L Ludgate, K Liu, L Luckenbaugh, N Streck… - Journal of …, 2016 - Am Soc Microbiol
Multiple subunits of the hepatitis B virus (HBV) core protein (HBc) assemble into an
icosahedral capsid that packages the viral pregenomic RNA (pgRNA). The N-terminal …
icosahedral capsid that packages the viral pregenomic RNA (pgRNA). The N-terminal …
The interface between hepatitis B virus capsid proteins affects self-assembly, pregenomic RNA packaging, and reverse transcription
Z Tan, K Pionek, N Unchwaniwala, ML Maguire… - Journal of …, 2015 - Am Soc Microbiol
Hepatitis B virus (HBV) capsid proteins (Cps) assemble around the pregenomic RNA
(pgRNA) and viral reverse transcriptase (P). pgRNA is then reverse transcribed to double …
(pgRNA) and viral reverse transcriptase (P). pgRNA is then reverse transcribed to double …
An RNA stem-loop structure directs hepatitis B virus genomic RNA encapsidation
JR Pollack, D Ganem - Journal of virology, 1993 - Am Soc Microbiol
Selective encapsidation of hepatitis B virus (HBV) genomic RNA within cytoplasmic core
particles requires recognition of the cis-encapsidation signal,(termed epsilon) located at the …
particles requires recognition of the cis-encapsidation signal,(termed epsilon) located at the …
[HTML][HTML] HBV RNA pre-genome encodes specific motifs that mediate interactions with the viral core protein that promote nucleocapsid assembly
Formation of the hepatitis B virus nucleocapsid is an essential step in the viral lifecycle, but
its assembly is not fully understood. We report the discovery of sequence-specific …
its assembly is not fully understood. We report the discovery of sequence-specific …
[HTML][HTML] Structural organization of pregenomic RNA and the carboxy-terminal domain of the capsid protein of hepatitis B virus
JCY Wang, MS Dhason, A Zlotnick - 2012 - journals.plos.org
The Hepatitis B Virus (HBV) double-stranded DNA genome is reverse transcribed from its
RNA pregenome (pgRNA) within the virus core (or capsid). Phosphorylation of the arginine …
RNA pregenome (pgRNA) within the virus core (or capsid). Phosphorylation of the arginine …
Localization of the C terminus of the assembly domain of hepatitis B virus capsid protein: implications for morphogenesis and organization of encapsidated RNA
A Zlotnick, N Cheng, SJ Stahl… - Proceedings of the …, 1997 - National Acad Sciences
The capsid protein of hepatitis B virus, consisting of an “assembly” domain (residues 1–149)
and an RNA-binding “protamine” domain (residues 150–183), assembles from dimers into …
and an RNA-binding “protamine” domain (residues 150–183), assembles from dimers into …
Hepatitis B virus core protein dephosphorylation occurs during pregenomic RNA encapsidation
Hepatitis B virus (HBV) core protein consists of an N-terminal assembly domain and a C-
terminal domain (CTD) with seven conserved serines or threonines that are dynamically …
terminal domain (CTD) with seven conserved serines or threonines that are dynamically …
Hepatitis B virus nucleocapsids formed by carboxy-terminally mutated core proteins contain spliced viral genomes but lack full-size DNA
J Köck, M Nassal, K Deres, HE Blum… - Journal of …, 2004 - Am Soc Microbiol
The carboxy-terminal sequence of the hepatitis B virus (HBV) core protein constitutes a
nucleic acid binding domain that is rich in arginine residues and contains three serine …
nucleic acid binding domain that is rich in arginine residues and contains three serine …