Key two‐component regulatory systems that control biofilm formation in Pseudomonas aeruginosa

H Mikkelsen, M Sivaneson… - Environmental …, 2011 - Wiley Online Library
Biofilm formation in P. aeruginosa is a highly regulated process that proceeds through a
number of distinct stages. This development is controlled by a wide range of factors, of which …

Surface Sensing for Biofilm Formation in Pseudomonas aeruginosa

CY Chang - Frontiers in microbiology, 2018 - frontiersin.org
Aggregating and forming biofilms on biotic or abiotic surfaces are ubiquitous bacterial
behaviors under various conditions. In clinical settings, persistent presence of biofilms …

A Novel Signaling Network Essential for Regulating Pseudomonas aeruginosa Biofilm Development

OE Petrova, K Sauer - PLoS pathogens, 2009 - journals.plos.org
The important human pathogen Pseudomonas aeruginosa has been linked to numerous
biofilm-related chronic infections. Here, we demonstrate that biofilm formation following the …

A spider web strategy of type IV pili‐mediated migration to build a fibre‐like Psl polysaccharide matrix in Pseudomonas aeruginosa biofilms

S Wang, MR Parsek, DJ Wozniak… - Environmental …, 2013 - Wiley Online Library
Bacterial motilities participate in biofilm development. However, it is unknown how/if
bacterial motility affects formation of the biofilm matrix. Psl polysaccharide is a key biofilm …

Distinct roles of extracellular polymeric substances in Pseudomonas aeruginosa biofilm development

L Yang, Y Hu, Y Liu, J Zhang… - Environmental …, 2011 - Wiley Online Library
Bacteria form surface attached biofilm communities as one of the most important survival
strategies in nature. Biofilms consist of water, bacterial cells and a wide range of self …

Flagellar and twitching motility are necessary for Pseudomonas aeruginosa biofilm development

GA O'Toole, R Kolter - Molecular microbiology, 1998 - Wiley Online Library
The formation of complex bacterial communities known as biofilms begins with the
interaction of planktonic cells with a surface in response to appropriate environmental …

Regulation of Biofilm Exopolysaccharide Biosynthesis and Degradation in Pseudomonas aeruginosa

LZ Ma, D Wang, Y Liu, Z Zhang… - Annual review of …, 2022 - annualreviews.org
Microbial communities enmeshed in a matrix of macromolecules, termed as biofilms, are the
natural setting of bacteria. Exopolysaccharide is a critical matrix component of biofilms …

Pseudomonas aeruginosa biofilm infections: From molecular biofilm biology to new treatment possibilities

T Tolker‐Nielsen - Apmis, 2014 - Wiley Online Library
Bacteria in natural, industrial and clinical settings predominantly live in biofilms, ie, sessile
structured microbial communities encased in self‐produced extracellular matrix material …

Assembly and Development of the Pseudomonas aeruginosa Biofilm Matrix

L Ma, M Conover, H Lu, MR Parsek, K Bayles… - PLoS …, 2009 - journals.plos.org
Virtually all cells living in multicellular structures such as tissues and organs are encased in
an extracellular matrix. One of the most important features of a biofilm is the extracellular …

Biofilm and Quorum sensing mediated pathogenicity in Pseudomonas aeruginosa

K Brindhadevi, F LewisOscar, E Mylonakis… - Process …, 2020 - Elsevier
The emergence of multidrug resistance has become an alarming and lifethreatening
phenomenon for humans. Various mechanisms are involved in the development of …