Iron-induced derangement in hepatic Δ-5 and Δ-6 desaturation capacity and fatty acid profile leading to steatosis: impact on extrahepatic tissues and prevention by …
C Barrera, R Valenzuela, MA Rincón… - … and Essential Fatty …, 2020 - Elsevier
The administration of iron induces liver oxidative stress and depletion of long-chain
polyunsaturated fatty acids (LCPUFAs), n-6/n-3 LCPUFA ratio enhancement and fat …
polyunsaturated fatty acids (LCPUFAs), n-6/n-3 LCPUFA ratio enhancement and fat …
Molecular mechanisms related to the hepatoprotective effects of antioxidant-rich extra virgin olive oil supplementation in rats subjected to short-term iron …
C Barrera, R Valenzuela, MÁ Rincón… - Free Radical Biology …, 2018 - Elsevier
Enhanced iron levels in liver are associated with oxidative stress development and damage
with increased fat accumulation. The aim of this work was to assess the hypothesis that …
with increased fat accumulation. The aim of this work was to assess the hypothesis that …
Iron-induced pro-oxidant and pro-lipogenic responses in relation to impaired synthesis and accretion of long-chain polyunsaturated fatty acids in rat hepatic and …
R Valenzuela, MÁ Rincón-Cervera, F Echeverría… - Nutrition, 2018 - Elsevier
Objectives Iron is involved in processes involving oxygen transfer and utilization. Excess
iron is linked to cardiovascular diseases and some types of cancer. Iron overload is …
iron is linked to cardiovascular diseases and some types of cancer. Iron overload is …
Supplementation with antioxidant-rich extra virgin olive oil prevents hepatic oxidative stress and reduction of desaturation capacity in mice fed a high-fat diet: Effects …
MA Rincón-Cervera, R Valenzuela… - Nutrition, 2016 - Elsevier
Objective The aim of this study was to assess the effect of dietary supplementation with extra
virgin olive oil (EVOO) in mice on the reduction of desaturase and antioxidant enzymatic …
virgin olive oil (EVOO) in mice on the reduction of desaturase and antioxidant enzymatic …
High-dose ferric citrate supplementation attenuates omega-3 polyunsaturated fatty acid biosynthesis via downregulating delta 5 and 6 desaturases in rats with high-fat …
A Faradina, SH Tseng, TH Tung, SY Huang, YC Lee… - Food & function, 2021 - pubs.rsc.org
Obesity is associated with an increased risk of an iron deficiency; however, a synergistic
relationship between iron and lipid homeostasis was also observed. The aim of this study …
relationship between iron and lipid homeostasis was also observed. The aim of this study …
Supplementation with docosahexaenoic acid and extra virgin olive oil prevents liver steatosis induced by a high‐fat diet in mice through PPAR‐α and Nrf2 …
MC Hernández‐Rodas, R Valenzuela… - Molecular Nutrition & …, 2017 - Wiley Online Library
Scope Nonalcoholic fatty liver disease is the most common cause of liver disease, for which
there is no validated drug therapy at present time. In this respect, the PUFA …
there is no validated drug therapy at present time. In this respect, the PUFA …
Anti-steatotic effects of an n-3 LCPUFA and extra virgin olive oil mixture in the liver of mice subjected to high-fat diet
R Valenzuela, A Espinosa, P Llanos… - Food & function, 2016 - pubs.rsc.org
Non-alcoholic fatty liver disease (NAFLD) is characterized by liver steatosis, oxidative stress,
and drastic depletion of n-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA), namely …
and drastic depletion of n-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA), namely …
Differential effect of high dietary iron on α-tocopherol and retinol levels in the liver and serum of mice fed olive oil–and corn oil–enriched diets
The influence of dietary fats on cellular α-tocopherol and retinol uptake in iron overload is
poorly understood. The aim of this study was to investigate the effect of a high-iron diet on …
poorly understood. The aim of this study was to investigate the effect of a high-iron diet on …
High fat diet induces liver steatosis and early dysregulation of iron metabolism in rats
This paper is dedicated to the memory of our wonderful colleague Professor Alfredo
Colonna, who passed away the same day of its acceptance. Fatty liver accumulation …
Colonna, who passed away the same day of its acceptance. Fatty liver accumulation …
Effects of olive oil and its fractions on oxidative stress and the liver's fatty acid composition in 2, 4-Dichlorophenoxyacetic acid-treated rats
A Nakbi, W Tayeb, A Grissa, M Issaoui, S Dabbou… - Nutrition & …, 2010 - Springer
Background Olive oil's beneficial effects are not only related to its high content of oleic acid,
but also to the antioxidant potential of its polyphenols. In this study, we assess the effects of …
but also to the antioxidant potential of its polyphenols. In this study, we assess the effects of …
相关搜索
- rat hepatic extrahepatic tissues
- rat hepatic fatty acids
- fatty acids extrahepatic tissues
- oil supplementation iron administration
- iron metabolism liver steatosis
- fat diet liver steatosis
- oxidative stress olive oil
- rat hepatic responses in relation
- iron metabolism fat diet
- rat hepatic impaired synthesis
- responses in relation extrahepatic tissues
- impaired synthesis extrahepatic tissues
- eicosapentaenoic acid tissue abnormalities
- responses in relation fatty acids
- impaired synthesis fatty acids