Frequency and phase correction for multiplexed edited MRS of GABA and glutathione

M Mikkelsen, MG Saleh, J Near… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose Detection of endogenous metabolites using multiplexed editing substantially
improves the efficiency of edited magnetic resonance spectroscopy. Multiplexed editing (ie …

Impact of frequency drift on gamma‐aminobutyric acid‐edited MR spectroscopy

AD Harris, B Glaubitz, J Near… - Magnetic resonance …, 2014 - Wiley Online Library
Purpose To investigate the quantitative impact of frequency drift on Gamma‐Aminobutyric
acid (GABA+)‐edited MRS of the human brain at 3 Tesla (T). Methods Three sequential …

Multi-vendor standardized sequence for edited magnetic resonance spectroscopy

MG Saleh, D Rimbault, M Mikkelsen, G Oeltzschner… - Neuroimage, 2019 - Elsevier
Spectral editing allows direct measurement of low-concentration metabolites, such as GABA,
glutathione (GSH) and lactate (Lac), relevant for understanding brain (patho) physiology …

Comparison of linear combination modeling strategies for edited magnetic resonance spectroscopy at 3 T

HJ Zöllner, S Tapper, SCN Hui, PB Barker… - NMR in …, 2022 - Wiley Online Library
J‐difference‐edited spectroscopy is a valuable approach for the in vivo detection of γ‐
aminobutyric‐acid (GABA) with magnetic resonance spectroscopy (MRS). A recent expert …

Effects of carrier frequency mismatch on frequency-selective spectral editing

L An, MF Araneta, C Johnson, J Shen - Magnetic Resonance Materials in …, 2019 - Springer
Objectives This study sought to investigate the effects of carrier frequency mismatch on
spectral editing and its correction by frequency matching of basis functions. Materials and …

Retrospective correction of frequency drift in spectral editing: The GABA editing example

JW van der Veen, S Marenco, KF Berman… - NMR in …, 2017 - Wiley Online Library
GABA levels can be measured using proton MRS with a two‐step editing sequence.
However due to the low concentration of GABA, long acquisition time is usually needed to …

Simultaneous edited MRS of GABA and glutathione

MG Saleh, G Oeltzschner, KL Chan, NAJ Puts… - Neuroimage, 2016 - Elsevier
Edited MRS allows the detection of low-concentration metabolites, whose signals are not
resolved in the MR spectrum. Tailored acquisitions can be designed to detect, for example …

Simultaneous edited MRS of GABA, glutathione, and ethanol

MG Saleh, M Wang, M Mikkelsen, SCN Hui… - NMR in …, 2020 - Wiley Online Library
The aim of this work was to develop simultaneous edited MRS of γ‐aminobutyric acid
(GABA), glutathione (GSH), and ethanol (EtOH) using Hadamard encoding and …

[HTML][HTML] Prospective frequency and motion correction for edited 1H magnetic resonance spectroscopy

A Marsman, A Lind, ET Petersen, M Andersen, VO Boer - Neuroimage, 2021 - Elsevier
The major inhibitory neurotransmitter gamma-aminobutyric acid (GABA) and the dominant
antioxidant glutathione (GSH) both play a crucial role in brain functioning and are involved …

Difference optimization: automatic correction of relative frequency and phase for mean non-edited and edited GABA 1H MEGA-PRESS spectra

M Cleve, M Krämer, A Gussew… - Journal of Magnetic …, 2017 - Elsevier
Phase and frequency corrections of magnetic resonance spectroscopic data are of major
importance to obtain reliable and unambiguous metabolite estimates as validated in recent …