Characteristics of patients with major depressive disorder switching SSRI/SNRI therapy compared with those augmenting with an atypical antipsychotic in a real-world …

DM Kern, MS Cepeda… - Current Medical …, 2021 - Taylor & Francis
Background Following a partial response of first-line antidepressant therapy for the
treatment of major depressive disorder (MDD), there is a choice to augment treatment with …

What happens next?: a claims database study of second-line pharmacotherapy in patients with major depressive disorder (MDD) who initiate selective serotonin …

S Ball, P Classi, EB Dennehy - Annals of general psychiatry, 2014 - Springer
Background The objective of this research was to examine treatment patterns and health-
care costs associated with second-step pharmacotherapy in patients with major depressive …

Nine-month predictors and outcomes of SSRI antidepressant continuation in primary care

JE Aikens, K Kroenke, RW Swindle… - General Hospital …, 2005 - Elsevier
BACKGROUND: This study aimed to identify the predictors and outcomes of SSRI
antidepressant continuation, discontinuation and switching over a 9-month period of …

Real-world determinants of adjunctive antipsychotic prescribing for patients with major depressive disorder and inadequate response to antidepressants: a case …

RS McIntyre, E Weiller - Advances in therapy, 2015 - Springer
Introduction Patients with major depressive disorder (MDD) often fail to respond to first-line
antidepressant treatments (ADTs); subsequent strategies include dosage increase, switch to …

Treatment of SSRI-resistant depression: a meta-analysis comparing within-versus across-class switches

GI Papakostas, M Fava, ME Thase - Biological psychiatry, 2008 - Elsevier
BACKGROUND: Two broad treatment options exist for switching antidepressants for
depressed patients who fail to respond to a selective serotonin reuptake inhibitor (SSRI) …

What to expect when switching to a second antidepressant medication following an ineffective initial SSRI: a report from the randomized clinical STAR* D study

AJ Rush, C South, MK Jha, SB Jain… - The Journal of clinical …, 2020 - psychiatrist.com
Objective: An antidepressant medication switch often follows a failed initial trial with
selective serotonin reuptake inhibitors (SSRIs). When, for whom, and how often second-step …

When discontinuing SSRI antidepressants is a challenge: management tips

MK Jha, AJ Rush, MH Trivedi - American Journal of …, 2018 - Am Psychiatric Assoc
Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed class of
antidepressant (1) and are recommended as one of the first-line treatments (2–4) for major …

[HTML][HTML] Real-world characteristics of European patients receiving SNRIs as first-line treatment for major depressive disorder

L Bartova, G Fugger, M Dold, A Kautzky… - Journal of affective …, 2023 - Elsevier
Background Serotonin-norepinephrine reuptake inhibitors (SNRIs) are among the most
frequently prescribed antidepressants (ADs) for major depressive disorder (MDD), with an …

Treatment patterns, healthcare resource utilization, and costs following first-line antidepressant treatment in major depressive disorder: a retrospective US claims …

G Gauthier, A Guérin, M Zhdanava, W Jacobson… - BMC psychiatry, 2017 - Springer
Background Although the symptoms of major depressive disorder (MDD) are often
manageable with pharmacotherapy, response to first-line antidepressant treatment is often …

Treatment patterns in major depressive disorder after an inadequate response to first-line antidepressant treatment

M Garcia-Toro, E Medina, JL Galan, MA Gonzalez… - BMC psychiatry, 2012 - Springer
Background The aim of the study was to determine the most common pharmacological
strategies used in the management of major depressive disorder (MDD) after an inadequate …