Characterization of peripheral immune events in primary colorectal cancer patients

C Lu - 2022 - edoc.ub.uni-muenchen.de
1.1 Colorectal Cancer 1.1. 1 The Nature of Colorectal Cancer Colorectal cancer (CRC) is the
third most frequent carcinoma and the second leading cause of cancer-associated death …

Immune response and colorectal cancer

D Tougeron, E Fauquembergue, JB Latouche - Bulletin du cancer, 2013 - europepmc.org
Immune response has a crucial role in the control of tumoral progression in colorectal
cancer (CRC). A close link between the rate of tumor infiltrating lymphocytes and prognosis …

Comprehensive molecular characterization of colorectal cancer reveals genomic predictors of immune cell infiltrates.

M Giannakis, S Shukla, JX Mu, R Nishihara… - 2015 - ascopubs.org
3505 Background: Colorectal cancer (CRC) is a molecularly heterogeneous disease that
arises and progresses in the context of a complex microenvironment. Tumor immune cell …

Immune cells in colorectal cancer: prognostic relevance and role of MSI

V Deschoolmeester, M Baay, F Lardon… - Cancer …, 2011 - Springer
There is growing evidence that both local and systemic inflammatory responses play an
important role in the progression of a variety of solid tumors. Colorectal cancer (CRC) results …

[HTML][HTML] Immunoprofiling of colitis-associated and sporadic colorectal cancer and its clinical significance

JS Soh, SI Jo, H Lee, E Do, SW Hwang, SH Park… - Scientific Reports, 2019 - nature.com
Immunoprofiling is useful for predicting prognosis in various malignancies and provides
targets for immunotherapy. Quantitative multispectral imaging system, which allows …

Characterization of an adaptive immune response in microsatellite-instable colorectal cancer

F Boissière-Michot, G Lazennec, H Frugier… - …, 2014 - Taylor & Francis
Sporadic or hereditary colorectal cancer (CRC) with microsatellite instability (MSI) is
frequently characterized by inflammatory lymphocytic infiltration and tends to be associated …

[HTML][HTML] Immune microenvironment in sporadic early-onset versus average-onset colorectal cancer

F Andric, A Al-Fairouzi, Y Wettergren, L Szeponik… - Cancers, 2023 - mdpi.com
Simple Summary The incidence of non-hereditary cancer in the left colon and rectum is
increasing in young patients worldwide for unknown reasons. To understand this …

[PDF][PDF] Tumor-immune interactions in colorectal cancer: link between the primary tumor and circulating immune cells

D Krijgsman - Leiden University, 2021 - scholarlypublications …
Colorectal cancer (CRC) is a major contributor to cancer-related morbidity and mortality,
accounting for approximately one million new cases per year throughout the world, with …

Immunology and immunotherapy in CRC

OJ Cordero, R Varela-Calviño, B Graña-Suárez… - … of Colorectal Cancer, 2022 - Elsevier
Almost 20 years have passed since the first consensus definition on the immune
characteristics of cancer, which included:(i) the progression of cancer occurs in a …

Immune checkpoints expression in MSI versus MSS colorectal cancers and their potential therapeutic implications.

NJ Llosa, F Housseau, EC Wick, L Hechenbleikner… - 2014 - ascopubs.org
3620 Background: Colorectal cancer (CRC) is divided into 2 groups based on genomic
differences: chromosomal instability (80%), and microsatellite instability (MSI)(20%). MSI …