[HTML][HTML] Cholesterol associated genetic risk score and acute coronary syndrome in Czech males

JA Hubacek, V Adamkova, V Lanska, V Staněk… - Molecular Biology …, 2024 - Springer
Background Despite a general decline in mean levels across populations, LDL-cholesterol
levels remain a major risk factor for acute coronary syndrome (ACS). The APOB, LDL-R …

[HTML][HTML] Association of genetic variants influencing lipid levels with coronary artery disease in Japanese individuals

F Takeuchi, M Isono, T Katsuya, M Yokota… - 2012 - journals.plos.org
Background/Objective In Japanese populations, we performed a replication study of genetic
loci previously identified in European-descent populations as being associated with lipid …

[HTML][HTML] CELSR2–PSRC1–SORT1 gene expression and association with coronary artery disease and plasma lipid levels in an Asian Indian cohort

P Arvind, J Nair, S Jambunathan, VV Kakkar… - Journal of …, 2014 - Elsevier
Background Genetic regulation of plasma lipids has been shown to influence the risk of
coronary artery disease (CAD). We analyzed the relationship between rs599839 and …

Genetic risk analysis of coronary artery disease in Pakistani subjects using a genetic risk score of 21 variants

SU Shahid, JA Cooper, KE Beaney, K Li, A Rehman… - Atherosclerosis, 2017 - Elsevier
Background and aims Conventional coronary artery disease (CAD) risk factors like age,
gender, blood lipids, hypertension and smoking have been the basis of CAD risk prediction …

Genetic predisposition to coronary heart disease and stroke using an additive genetic risk score: a population-based study in Greece

N Yiannakouris, M Katsoulis, V Dilis, LD Parnell… - Atherosclerosis, 2012 - Elsevier
OBJECTIVE: To determine the extent to which the risk for incident coronary heart disease
(CHD) increases in relation to a genetic risk score (GRS) that additively integrates the …

[HTML][HTML] Effect of SORT1, APOB and APOE polymorphisms on LDL-C and coronary heart disease in Pakistani subjects and their comparison with Northwick Park …

SU Shahid, ᅟShabana, JA Cooper… - Lipids in health and …, 2016 - Springer
Abstract Background Many SNPs have been identified in genes regulating LDL-C
metabolism, but whether their influence is similar in subjects from different ethnicities is …

[HTML][HTML] Association of variants in CELSR2-PSRC1-SORT1 with risk of serum lipid traits, coronary artery disease and ischemic stroke

YJ Zhou, SC Hong, Q Yang, RX Yin… - … journal of clinical and …, 2015 - ncbi.nlm.nih.gov
Recent genome-wide association studies (GWAS) have identified genetic variants
associated with coronary artery disease (CAD), ischemic stroke (IS) and serum lipid traits in …

rs629301 CELSR2 polymorphism confers a ten-year equivalent risk of critical stenosis assessed by coronary angiography

D Noto, AB Cefalù, N Martinelli, A Giammanco… - Nutrition, Metabolism …, 2021 - Elsevier
Background and aims Novel genetic determinants associated with coronary artery disease
(CAD) have been discovered by genome wide association studies. Variants encompassing …

Genetic risk scores predict recurrence of acute coronary syndrome

S Vaara, E Tikkanen, O Parkkonen… - Circulation …, 2016 - Am Heart Assoc
Background—Several clinical risk estimation tools have established their role in the
prediction of recurrence of acute coronary syndrome (ACS), but the value of genetic risk …

Genetic score based on high-risk genetic polymorphisms and early onset of ischemic heart disease in an Italian cohort of ischemic patients

C Vecoli, D Adlerstein, E Shehi, F Bigazzi… - Thrombosis research, 2014 - Elsevier
Several single-nucleotide polymorphisms (SNPs) have been recognized as associated with
ischemic heart disease (IHD) although the optimal set of risk genotypes has not be …