Concise synthesis of guanidine-containing heterocycles using the Biginelli reaction
BL Nilsson, LE Overman - The Journal of organic chemistry, 2006 - ACS Publications
Two general methods for the synthesis of 2-imino-5-carboxy-3, 4-dihydropyrimidines were
developed using the three-component Biginelli reaction. The first method utilizes pyrazole …
developed using the three-component Biginelli reaction. The first method utilizes pyrazole …
Unprecedented single-pot protocol for the synthesis of N1, C6-linked bicyclic 3, 4-dihydropyrimidinones via lithiation of Biginelli compounds
4-Aryl/alkyl-6-methyl-3, 4-dihydropyrimidin-2 (1H)-one ester derivatives readily undergo
metalation at the C6 methyl (vinylogous ester) position along with two acidic NHs upon …
metalation at the C6 methyl (vinylogous ester) position along with two acidic NHs upon …
Total synthesis of (−)-crambidine and definition of the relative configuration of its unique tetracyclic guanidinium core
LE Overman, YH Rhee - Journal of the American Chemical …, 2005 - ACS Publications
Total syntheses of the 3 S, 8 S, 10 S, 19 R, 43 S isomer 4a and the 3 S, 8 S, 10 S, 19 R, 43 R
isomer 4b of the unique crambescidin alkaloid crambidine are reported. These studies …
isomer 4b of the unique crambescidin alkaloid crambidine are reported. These studies …
Polyphosphate ester-mediated synthesis of dihydropyrimidines. Improved conditions for the Biginelli reaction
CO Kappe, SF Falsone - Synlett, 1998 - thieme-connect.com
Dihydropyrimidines 7 are prepared in high yield by a one-pot condensation of aldehydes,
acetoacetates, and ureas using a polyphosphate ester-mediated cyclocondensation …
acetoacetates, and ureas using a polyphosphate ester-mediated cyclocondensation …
[PDF][PDF] One-pot synthesis of 5-carboxanilide-dihydropyrimidinones using etidronic Acid
One-pot synthesis of 5-carboxanilide-dihydropyrimidinones using etidronic Acid Page 1
General Papers ARKIVOC 2009 (vii) 79-85 One-pot synthesis of 5-carboxanilide-dihydropyrimidinones …
General Papers ARKIVOC 2009 (vii) 79-85 One-pot synthesis of 5-carboxanilide-dihydropyrimidinones …
A One‐Pot Biginelli Synthesis of 6‐Unsubstituted 5‐Aroylpyrimidin‐2(1H)‐ones and 6‐Acetyl‐1,2,4‐triazin‐3(2H)‐ones
ES Darwish, I Abdelshafy Abdelhamid… - Helvetica Chimica …, 2010 - Wiley Online Library
The three‐component Biginelli‐like cyclocondensation reaction of enamines 1, urea, and
aldehydes in dioxane/acetic acid efficiently afforded the corresponding 6‐unsubstituted 3, 4 …
aldehydes in dioxane/acetic acid efficiently afforded the corresponding 6‐unsubstituted 3, 4 …
Development of a [3+ 3] approach to tetrahydropyridines and its application in indolizidine alkaloid synthesis
LC Pattenden, H Adams, SA Smith, JPA Harrity - Tetrahedron, 2008 - Elsevier
Development of a [3+3] approach to tetrahydropyridines and its application in indolizidine
alkaloid synthesis - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & …
alkaloid synthesis - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & …
The tethered Biginelli condensation in natural product synthesis
ZD Aron, LE Overman - Chemical communications, 2004 - pubs.rsc.org
The tethered Biginelli condensation in natural product synthesis - Chemical
Communications (RSC Publishing) DOI:10.1039/B309910E Royal Society of Chemistry …
Communications (RSC Publishing) DOI:10.1039/B309910E Royal Society of Chemistry …
A piperidinium triflate catalyzed Biginelli reaction
C Ramalingan, SJ Park, IS Lee, YW Kwak - Tetrahedron, 2010 - Elsevier
A piperidinium triflate catalyzed Biginelli reaction - ScienceDirect Skip to main contentSkip to
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Synthesis of 5-aroyldihydropyrimidinones via Liebeskind-Srogl thiol ester-boronic acid cross-couplings
H Prokopcova, L Pisani, CO Kappe - Synlett, 2007 - thieme-connect.com
A novel and efficient two-step synthesis of 5-aroyl-3, 4-dihydropyrimidin-2-ones is reported.
These privileged ketone structures are readily generated by microwave-assisted Liebeskind …
These privileged ketone structures are readily generated by microwave-assisted Liebeskind …