[HTML][HTML] Fluorine-18 labeled amino acids for tumor PET/CT imaging

Y Qi, X Liu, J Li, H Yao, S Yuan - Oncotarget, 2017 - ncbi.nlm.nih.gov
Tumor glucose metabolism and amino acid metabolism are usually enhanced, 18 F-FDG for
tumor glucose metabolism PET imaging has been clinically well known, but tumor amino …

An overview of radiolabeled amino acid tracers in oncologic imaging

S Jain, VK Dhingra - Frontiers in Oncology, 2023 - frontiersin.org
Molecular imaging has witnessed a great progress in the field of oncology over the past few
decades. Radiolabeled amino acid (AA) tracers are particularly helpful in the areas where …

Fluorine-18 labeled amino acids for oncologic imaging with positron emission tomography

C Huang, J McConathy - Current topics in medicinal chemistry, 2013 - ingentaconnect.com
18F-labeled amino acids are an important class of imaging agents for positron emission
tomography (PET) that target the increased rates of amino acid transport by many tumor …

Fluorinated amino acids for tumour imaging with positron emission tomography

P Laverman, OC Boerman, FH Corstens… - European journal of …, 2002 - Springer
The currently preferred radiopharmaceutical for positron emission tomography (PET) in
oncology is 2-[18 F] fluoro-deoxyglucose (FDG). Increased accumulation of this …

4-[18F]Fluoroglutamic Acid (BAY 85-8050), a New Amino Acid Radiotracer for PET Imaging of Tumors: Synthesis and in Vitro Characterization

RN Krasikova, OF Kuznetsova… - Journal of medicinal …, 2011 - ACS Publications
There is a high demand for tumor specific PET tracers in oncology imaging. Besides
glucose, certain amino acids also serve as energy sources and anabolic precursors for …

Carbon-11 and fluorine-18 labeled amino acid tracers for positron emission tomography imaging of tumors

A Sun, X Liu, G Tang - Frontiers in chemistry, 2018 - frontiersin.org
Tumor cells have an increased nutritional demand for amino acids (AAs) to satisfy their rapid
proliferation. Positron-emitting nuclide labeled AAs are interesting probes and are of great …

Improving amino acid imaging: Hungry or stuffed?

PL Jager - Journal of Nuclear Medicine, 2002 - Soc Nuclear Med
With the increasing clinical application of FDG PET, interest in metabolic imaging in general
is growing among clinicians. The reasons for the great impact that FDG PET is currently …

Clinical impact of amino acid PET in gliomas

WD Heiss - Journal of Nuclear Medicine, 2014 - Soc Nuclear Med
With an incidence of 20.5 per 100,000 people each year, tumors of the central nervous
system are a heterogeneous group, with meningiomas (35.5%) and gliomas (30%) being …

Evaluation of 3-l- and 3-d-[18F]Fluorophenylalanines as PET Tracers for Tumor Imaging

F Krämer, B Gröner, C Hoffmann, A Craig, M Brugger… - Cancers, 2021 - mdpi.com
Simple Summary The early detection and treatment of malignant brain tumors can
significantly improve the survival time and life quality of affected patients. Whereas positron …

[PDF][PDF] Applications of PET imaging of neurological tumors with radiolabeled amino acids

N Galldiks, KJ Langen - The Quarterly Journal of Nuclear Medicine …, 2015 - researchgate.net
Routine diagnostics and treatment monitoring of brain tumors is usually based on contrast-
enhanced magnetic resonance imaging (MRI). However, the capacity of structural MRI to …