Background Previously, we showed that the tetraspanin membrane protein CD63 mediates
both early and post-integration stages of the HIV-1 replication cycle. The temporal roles of …

Macrophages and CD4+ lymphocytes are the major reservoirs for HIV-1 infection. CD63 is a
tetraspanin transmembrane protein, which has been shown to play an essential role during …

During the assembly of human immunodeficiency virus type 1 (HIV-1) particles, the
tetraspanin CD63 can be incorporated into the viral membrane. Indeed, cell surface …

Macrophages and CD4+ T-cells are the major reservoirs for HIV-1 infection. CD63 is a
tetraspanin transmembrane protein, which has been shown to play an essential role during …

Background HIV-1 uses cellular co-factors for virion formation and release. The virus is able
to incorporate into the viral particles host cellular proteins, such as tetraspanins which could …

Human immunodeficiency virus type 1 (HIV-1) persists lifelong in infected individuals and
has evolved unique strategies in order to evade the immune system. One of these strategies …

Background The presence of the tetraspanins CD9, CD63, CD81 and CD82 at HIV-1
budding sites, at the virological synapse (VS), and their enrichment in HIV-1 virions has …

Human immunodeficiency virus type 1 (HIV-1) transmission takes place primarily through
cell-cell contacts known as virological synapses. Formation of these transient adhesions …

Accumulating evidence indicates that human immunodeficiency virus type 1 (HIV-1)
acquires various cellular membrane proteins in the lipid bilayer of the viral envelope …

Despite the great research effort placed during the last decades in HIV-1 study, still some
aspects of its replication cycle remain unknown. All this powerful research has succeeded in …