Dietary intake and risk assessment of phototoxic furocoumarins in humans

J Schlatter, B Zimmerli, R Dick, R Panizzon… - Food and chemical …, 1991 - Elsevier
The question of whether the furocoumarin content of vegetables is sufficient to induce
phototoxic skin reactions after ultraviolet irradiation was examined in two experiments with …

Dietary exposure to furocoumarins

DJ Wagstaff - Regulatory Toxicology and Pharmacology, 1991 - Elsevier
Natural furocoumarins, some of which are carcinogenic, are widespread components of the
diet which are frequently consumed. Because of the paucity of samples, the wide scatter of …

Limettin and furocoumarins in beverages containing citrus juices or extracts

E Gorgus, C Lohr, N Raquet, S Guth… - Food and chemical …, 2010 - Elsevier
Phototoxic and photo-genotoxic furocoumarins occur, eg, in citrus species, parsnip, parsley,
celery, and figs. They exhibit phototoxic and photo-genotoxic properties in combination with …

Toxicological assessment of furocoumarins in foodstuffs.

G Eisenbrand - 2007 - cabidigitallibrary.org
This article presents the shortened version of the opinion of the Senate Commission on
Food Safety of the German Research Foundation, which has studied toxicological …

Dietary furocoumarins and skin cancer: A review of current biological evidence

MM Melough, OK Chun - Food and chemical toxicology, 2018 - Elsevier
Furocoumarins are a class of compounds produced by several plant species, including
some popularly consumed by humans. Furocoumarins are known to be well absorbed from …

Relative photomutagenicity of furocoumarins and limettin in the hypoxanthine phosphoribosyl transferase assay in V79 cells

N Raquet, D Schrenk - Chemical research in toxicology, 2009 - ACS Publications
Furocoumarins are phototoxic and photomutagenic natural plant constituents found in many
medicinal plants and food items. Because plants contain mixtures of several furocoumarins …

Absence of phototoxicity/photoirritation potential of bergamottin determined In Vitro using OECD TG 432

M Cluzel, G Hais, A Irizar, V Lenouvel, JF Nash… - Regulatory Toxicology …, 2022 - Elsevier
The phototoxic potential of a number of furocoumarins is well established. On the other
hand, studies have shown that bergamottin, a furocoumarin containing a bulky, hydrophobic …

Identification and quantitation of furocoumarins in popularly consumed foods in the US using QuEChERS extraction coupled with UPLC-MS/MS analysis

MM Melough, SG Lee, E Cho, K Kim… - Journal of agricultural …, 2017 - ACS Publications
Furocoumarins are a class of photoactive compounds found in several plant species and
may be responsible for the observed association between consumption of citrus products …

Major furocoumarins in grapefruit juice I: levels and urinary metabolite (s)

A Messer, A Nieborowski, C Strasser, C Lohr… - Food and chemical …, 2011 - Elsevier
Furocoumarins are phototoxic and photogenotoxic natural plant constituents occurring in
cosmetics, food and drugs. Grapefruit juice is considered as a major dietary source of …

Furocoumarins: A review of biochemical activities, dietary sources and intake, and potential health risks

MM Melough, E Cho, OK Chun - Food and chemical toxicology, 2018 - Elsevier
Furocoumarins are a class of chemical compounds with phototoxic properties found
naturally in many plant species, including some commonly consumed by humans (Dolan et …