Extracellular vesicles: emerging roles in developing therapeutic approach and delivery tool of Chinese herbal medicine for the treatment of depressive disorder

Q Wu, WZ Duan, JB Chen, XP Zhao, XJ Li… - Frontiers in …, 2022 - frontiersin.org
Extracellular vesicles (EVs) are lipid bilayer-delimited particles released by cells, which play
an essential role in intercellular communication by delivering cellular components including …

The roles of extracellular vesicles in major depressive disorder

Y Li, Y Gui, M Zhao, X Chen, H Li, C Tian… - Frontiers in …, 2023 - frontiersin.org
Major depressive disorder (MDD) is a serious mental disease characterized by depressed
mood, loss of interest and suicidal ideation. Its rising prevalence has rendered MDD one of …

Extracellular vesicle–based drug delivery system boosts phytochemicals' therapeutic effect for neurodegenerative diseases

Z Zhu, L Liao, H Qiao - Acupuncture and Herbal Medicine, 2022 - journals.lww.com
Neurodegenerative diseases (NDs) are a major threat to the elderly, and efficient therapy is
rarely available. A group of phytochemicals has been shown to ameliorate NDs; however …

Therapeutic potential and pharmacological significance of extracellular vesicles derived from traditional medicinal plants

P Wu, W Wu, S Zhang, J Han, C Liu, H Yu… - Frontiers in …, 2023 - frontiersin.org
Medicinal plants are the primary sources for the discovery of novel medicines and the basis
of ethnopharmacological research. While existing studies mainly focus on the chemical …

Unlocking the Medicinal Potential of Plant-Derived Extracellular Vesicles: current Progress and Future Perspectives

X Liu, K Lou, Y Zhang, C Li, S Wei… - International Journal of …, 2024 - Taylor & Francis
Botanical preparations for herbal medicine have received more and more attention from
drug researchers, and the extraction of active ingredients and their successful clinical …

[HTML][HTML] Plant-derived extracellular vesicles-a novel clinical anti-inflammatory drug carrier worthy of investigation

M Shao, X Jin, S Chen, N Yang, G Feng - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Plant-derived extracellular vesicles (PDEVs) have shown remarkable potential as
sustainable, green, and efficient drug delivery nanocarriers. As natural nanoparticles …

[HTML][HTML] Extracellular vesicles in mental disorders: a state-of-art review

L Kong, D Zhang, S Huang, J Lai, L Lu… - … journal of biological …, 2023 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are nanoscale particles with various physiological functions
including mediating cellular communication in the central nervous system (CNS), which …

Focusing on future applications and current challenges of plant derived extracellular vesicles

Y Wang, J Wang, J Ma, Y Zhou, R Lu - Pharmaceuticals, 2022 - mdpi.com
Plant derived extracellular vesicles (EVs) are nano-sized membranous vesicles released by
plant cells, which contain lipids, proteins, nucleic acids and specific pharmacologically …

[HTML][HTML] Trends in the biological functions and medical applications of extracellular vesicles and analogues

Y Zhao, X Li, W Zhang, L Yu, Y Wang, Z Deng… - … Pharmaceutica Sinica B, 2021 - Elsevier
Natural extracellular vesicles (EVs) play important roles in many life processes such as in
the intermolecular transfer of substances and genetic information exchanges. Investigating …

Stem cell-derived extracellular vesicles: a promising nano delivery platform to the brain?

Y Guo, D Hu, L Lian, L Zhao, M Li, H Bao… - Stem cell reviews and …, 2023 - Springer
A very important cause of the frustration with drug therapy for central nervous system (CNS)
diseases is the failure of drug delivery. The blood–brain barrier (BBB) prevents most …