The article provides an overview of modern concepts of induced sputum analysis and a
description of the methodology and protocols for the collection of induced sputum in adults …

In recent years induced sputum analysis has become a non-invasive method for the
assessment of airway inflammation in obstructive airway diseases. Sputum induction is safe …

Background Infiltration of the airways mucosa with activated inflammatory cells appears to
be a major factor in the pathogenesis of asthma and other airway diseases. Examination of …

During recent years there has been a growing interest in using non-invasive biomarkers to
understand and monitor the airway inflammation in subjects with respiratory tract disorders …

Analysis of the proportions of eosinophils and neutrophils in induced sputum of asthmatic
patients allows inflammatory phenotyping which can inform prognosis and treatment. Other …

Background The technique of induced sputum has allowed to subdivide asthma patients into
inflammatory phenotypes according to their level of granulocyte airway infiltration. There are …

During recent years interest has been growing in the use of non-invasive methods for the
assessment of airway inflammation in subjects with asthma. to date sputum induction is the …

Cellular analysis of sputum either spontaneous or by induced sputum technique, has
become a widespread tool for the evaluation and guidance of treatment of inflammatory …

Background Assessment of airway inflammation via induced sputum cell count is a valuable
asset in asthma management. Treatment strategies based on it reduce exacerbations …

Background and objective Determination of asthma phenotypes, particularly inflammatory
phenotypes, helps guide treatment and management of this heterogeneous disease …