The convergent endeavors of the neuroscientist to establish a link between clinical
neurology, genetics, loss of function of an important protein, and channelopathies behind …

In the last decade, advances in molecular genetics and cellular electrophysiology have
increased our understanding of ion channel function. A number of diseases termed …

Ion channels are membrane proteins expressed in almost all living cells. The sequencing of
the human genome has identified more than 400 putative ion channels, but only a fraction of …

The birth and discovery of electrophysiological science took place in the 18 th century laying
the path for our understanding of nerve membrane ionic currents. The pore-forming proteins …

Ion channels are protein molecules that span across the cell membrane allowing the
passage of ions from one side of the membrane to the other. They have an aqueous pore …

In the human genome more than 400 genes encode ion channels, which are
transmembrane proteins mediating ion fluxes across membranes. Being expressed in all …

Ion channels are key molecules for signal transduction across biological membranes.
Combining physiological experiments with DNA sequence data has recently linked many …

Ion channels are macromolecular proteins that form water-filled pores in cell membranes
and they are critical for a variety of physiological and pharmacological functions …

Ion channels are intimately involved in the everyday physiological functions that enable us
to live a full and varied life. When disease strikes, malfunction of ion channels or their …

Ion channels are membrane proteins that act as gated pathways for the movement of ions
across cell membranes. They play essential roles in the physiology of all cells. In recent …