Distinct stages in stress granule assembly and disassembly
Stress granules are non-membrane bound RNA-protein (RNP) assemblies that form when
translation initiation is limited and contain a biphasic structure with stable core structures …
translation initiation is limited and contain a biphasic structure with stable core structures …
[PDF][PDF] G3BP1 is a tunable switch that triggers phase separation to assemble stress granules
The mechanisms underlying ribonucleoprotein (RNP) granule assembly, including the basis
for establishing and maintaining RNP granules with distinct composition, are unknown. One …
for establishing and maintaining RNP granules with distinct composition, are unknown. One …
[HTML][HTML] The integral role of RNA in stress granule formation and function
D Campos-Melo, ZCE Hawley… - Frontiers in Cell and …, 2021 - frontiersin.org
Stress granules (SGs) are phase-separated, membraneless, cytoplasmic ribonucleoprotein
(RNP) assemblies whose primary function is to promote cell survival by condensing …
(RNP) assemblies whose primary function is to promote cell survival by condensing …
Principles and properties of stress granules
DSW Protter, R Parker - Trends in cell biology, 2016 - cell.com
Stress granules are assemblies of untranslating messenger ribonucleoproteins (mRNPs)
that form from mRNAs stalled in translation initiation. Stress granules form through …
that form from mRNAs stalled in translation initiation. Stress granules form through …
[PDF][PDF] RNA-induced conformational switching and clustering of G3BP drive stress granule assembly by condensation
J Guillén-Boixet, A Kopach, AS Holehouse, S Wittmann… - Cell, 2020 - cell.com
Stressed cells shut down translation, release mRNA molecules from polysomes, and form
stress granules (SGs) via a network of interactions that involve G3BP. Here we focus on the …
stress granules (SGs) via a network of interactions that involve G3BP. Here we focus on the …
RNA self-assembly contributes to stress granule formation and defining the stress granule transcriptome
B Van Treeck, DSW Protter… - Proceedings of the …, 2018 - National Acad Sciences
Stress granules are higher order assemblies of nontranslating mRNAs and proteins that
form when translation initiation is inhibited. Stress granules are thought to form by protein …
form when translation initiation is inhibited. Stress granules are thought to form by protein …
[HTML][HTML] Molecular mechanisms of stress granule assembly and disassembly
S Hofmann, N Kedersha, P Anderson… - Biochimica et Biophysica …, 2021 - Elsevier
Stress granules (SGs) are membrane-less ribonucleoprotein (RNP)-based cellular
compartments that form in the cytoplasm of a cell upon exposure to various environmental …
compartments that form in the cytoplasm of a cell upon exposure to various environmental …
Isolation of yeast and mammalian stress granule cores
Stress granules are dynamic, conserved RNA-protein (RNP) assemblies that form when
translation is limiting; and are related to pathological aggregates in degenerative disease …
translation is limiting; and are related to pathological aggregates in degenerative disease …
Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules
RNA-protein (RNP) granules have been proposed to assemble by forming solid RNA/protein
aggregates or through phase separation into a liquid RNA/protein phase. Which model …
aggregates or through phase separation into a liquid RNA/protein phase. Which model …
mRNP architecture in translating and stress conditions reveals an ordered pathway of mRNP compaction
Stress granules (SGs) are transient membraneless organelles of nontranslating mRNA–
protein complexes (mRNPs) that form during stress. In this study, we used multiple single …
protein complexes (mRNPs) that form during stress. In this study, we used multiple single …