Traditional Chinese medicine plays a significant role in the treatment of various diseases
and has attracted increasing attention for clinical applications. Vascular diseases affecting …

Cardiovascular diseases (CVD) are the leading cause of death in the world. However, due
to the limited effectiveness and potential adverse effects of current treatments, the long-term …

Atherosclerosis is an epidemic across the globe [A1], and its morbidity and mortality remain
high, involving various complications and poor prognoses. In atherosclerosis, endothelial …

Berberine is a quaternary ammonium salt from the protoberberine group of isoquinoline
alkaloids found in such plants as gender Berberis. Berberine is recognised to improve …

Berberine, an isoquinoline alkaloid isolated from the Chinese herb Coptis chinensis and
other Berberis plants, has a wide range of pharmacological properties. Berberine can be …

Elevated levels of plasma cholesterol, impaired vascular wall, and presence of inflammatory
macrophages are important atherogenic risk factors contributing to atherosclerotic plaque …

In the last few decades, traditional natural products have been the center of attention for the
scientific community and exploration of their therapeutic abilities is proceeding perpetually …

Introduction: A number of plant-derived agents are used in many therapeutic areas.
Berberine, an important protoberberine alkaloid, is present in a number of medicinal plants …

Although advances have been made, chemotherapy for chronic, multifactorial diseases such
as cancers, Alzheimer's disease, cardiovascular diseases and diabetes is far from …

Berberine (BBR) has been confirmed to have multiple bioactivities in clinic, such as
cholesterol-lowering, anti-diabetes, cardiovascular protection and anti-inflammation …