The differential expression of transcription factors during embryonic development has been
selected as the main feature to define the specific subclasses of spinal interneurons …

Spinal cord injury (SCI) with consecutive paralysis below the lesion level is a severe
disorder affecting the patient for the rest of his or her life. So far, there is no known …

Spinal interneurons are important facilitators and modulators of motor, sensory, and
autonomic functions in the intact CNS. This heterogeneous population of neurons is now …

The spinal cord is comprised of four types of neurons: motor neurons, pre-ganglionic
neurons, ascending projection neurons, and spinal interneurons. Interneurons are neurons …

Severe spinal cord injury in adults leads to irreversible paralysis below the lesion. However,
adult rodents that received a complete thoracic lesion just after birth demonstrate proficient …

In order to use electrical stimulation or biological repair to attempt to alleviate spinal cord
dysfunction, a key problem will be how to target the intervention. Since the majority of inputs …

Propriospinal interneurons (INs) communicate information over short and long distances
within the spinal cord. They act to coordinate different parts of the body by linking motor …

Background Spinal interneurons have emerged as crucial targets of supraspinal input
during post-injury axonal remodelling. For example, lesioned corticospinal projections use …

Spinal cord injury (SCI) disrupts communication between the brain-derived descending
commands and the intraspinal circuits, the central pattern generator (CPG), that execute …

Traumatic spinal cord injury (SCI) impedes signal transmission by disrupting both the local
neurons and their surrounding synaptic connections. Although the majority of SCI patients …