Normothermic Ex Vivo Heart Perfusion with Mesenchymal Stem Cell‐Derived Conditioned Medium Improves Myocardial Tissue Protection in Rat Donation after …

Z Zeng, L Xu, Y Xu, Y Ruan, D Liu, J Li… - Stem Cells …, 2022 - Wiley Online Library
Objective. Adopting hearts from donation after circulatory death (DCD) is a promising
approach to enlarge the donor pool. Nevertheless, DCD hearts experience severe warm …

Donor heart preservation with hypoxic-conditioned medium-derived from bone marrow mesenchymal stem cells improves cardiac function in a heart transplantation …

P Zhou, H Liu, X Liu, X Ling, Z Xiao, P Zhu… - Stem Cell Research & …, 2021 - Springer
Background In heart transplantation, donor hearts inevitably suffer from
ischemia/reperfusion (I/R) injury, which leads to primary graft dysfunction and affects …

Hypothermic perfusion of donor heart with a preservation solution supplemented by mesenchymal stem cells

S Korkmaz-Icöz, S Li, R Hüttner, M Ruppert… - The Journal of Heart and …, 2019 - Elsevier
BACKGROUND Heart transplantation is the definitive treatment for end-stage heart failure. A
shortage of donor hearts forced transplant programs to accept older donors and longer …

A Novel Rat Model of Cardiac Donation After Circulatory Death Combined With Normothermic ex situ Heart Perfusion

J Li, C Xue, X Ling, Y Xie, D Pavan, H Chen… - Frontiers in …, 2021 - frontiersin.org
Background: In heart transplantation, the adoption of hearts from donation after circulatory
death (DCD) is considered to be a promising approach to expanding the donor pool …

Controlled reperfusion strategies improve cardiac hemodynamic recovery after warm global ischemia in an isolated, working rat heart model of donation after …

E Farine, P Niederberger, RK Wyss… - Frontiers in …, 2016 - frontiersin.org
Aims: Donation after circulatory death (DCD) could improve cardiac graft availability, which
is currently insufficient to meet transplant demand. However, DCD organs undergo an …

Bone marrow mesenchymal stem cells combine with normothermic machine perfusion to improve rat donor liver quality—the important role of hepatic microcirculation …

L Yang, H Cao, D Sun, B Hou, L Lin, ZY Shen… - Cell and tissue …, 2020 - Springer
Donation after circulatory death (DCD) can expand the donor pool effectively. A gap remains
in outcome between DCD livers and living donor livers, warranting improved DCD liver …

[HTML][HTML] Mesenchymal stem cell secretions improve donor heart function following ex vivo cold storage

M Wang, L Yan, Q Li, Y Yang, M Turrentine… - The Journal of thoracic …, 2022 - Elsevier
Objectives Heart transplantation is the gold standard of treatments for end-stage heart
failure, but its use is limited by extreme shortage of donor organs. The time “window” …

Cytoprotective effects of mesenchymal stem cells during liver transplantation from donors after cardiac death in rats

H Sasajima, S Miyagi, Y Kakizaki, T Kamei… - Transplantation …, 2018 - Elsevier
Background Liver transplantation from donors after cardiac death (DCD) might increase the
pool of available organs. Recently, some investigators reported the potential use of …

Cytoprotective effects of mesenchymal stem cells during liver transplantation from donors after cardiac death in swine

H Sasajima, S Miyagi, S Yamada, Y Kakizaki… - Transplantation …, 2020 - Elsevier
Background Liver transplantation from donors after cardiac death (DCDs) can increase the
pool of available organs. Recently, mesenchymal stem cells (MSCs) have been used to treat …

[HTML][HTML] Machine perfusion of donor heart with normothermic blood versus hypothermic HTK in preserving coronary endothelium in a porcine model of DCD

P Zhou, X Liu, Z Xiao, R Xu, X Lin, P Zhu… - Annals of Palliative …, 2020 - apm.amegroups.org
Background: Both machine perfusion (MP) of donor hearts with autologous blood and
crystalloid perfusates have advantages and disadvantages. Currently, which of the …