Does COVID19 infect the brain? If so, smokers might be at a higher risk

N Kabbani, JL Olds - Molecular pharmacology, 2020 - ASPET
COVID19 is a devastating global pandemic with epicenters in China, Italy, Spain, and now
the United States. While the majority of infected cases appear mild, in some cases …

SARS-CoV-2, more than a respiratory virus: its potential role in neuropathogenesis

CMS Singal, P Jaiswal, P Seth - ACS chemical neuroscience, 2020 - ACS Publications
The coronavirus disease-19 (COVID-19) pandemic has emerged as one of the major
outbreaks to be mentioned in history in coming times. Like severe acute respiratory …

Evidence of the COVID-19 virus targeting the CNS: tissue distribution, host–virus interaction, and proposed neurotropic mechanisms

AM Baig, A Khaleeq, U Ali, H Syeda - ACS chemical neuroscience, 2020 - ACS Publications
The recent outbreak of coronavirus infectious disease 2019 (COVID-19) has gripped the
world with apprehension and has evoked a scare of epic proportion regarding its potential to …

Central nervous system targets and routes for SARS-CoV-2: current views and new hypotheses

FJ Barrantes - ACS chemical neuroscience, 2020 - ACS Publications
As the coronavirus disease 2019 (COVID-19) pandemic unfolds, neurological signs and
symptoms reflect the involvement of targets beyond the primary lung effects. The etiological …

Neurological insights of COVID-19 pandemic

G Das, N Mukherjee, S Ghosh - ACS chemical neuroscience, 2020 - ACS Publications
The novel coronavirus SARS-CoV-2, which was identified after a recent outbreak in Wuhan,
China, in December 2019, has kept the whole world in tenterhooks due to its severe life …

The spatial and cell-type distribution of SARS-CoV-2 receptor ACE2 in the human and mouse brains

R Chen, K Wang, J Yu, D Howard, L French… - Frontiers in …, 2021 - frontiersin.org
By engaging angiotensin-converting enzyme 2 (ACE2 or Ace2), the novel pathogenic
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) invades host cells and …

Neuroinvasion of SARS-CoV-2 in human and mouse brain

E Song, C Zhang, B Israelow, A Lu-Culligan… - Journal of Experimental …, 2021 - rupress.org
Although COVID-19 is considered to be primarily a respiratory disease, SARS-CoV-2 affects
multiple organ systems including the central nervous system (CNS). Yet, there is no …

SARS-CoV-2 infectivity and neurological targets in the brain

WJ Lukiw, A Pogue, JM Hill - Cellular and molecular neurobiology, 2022 - Springer
The gateway for invasion by the novel severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) into human host cells is via the angiotensin-converting enzyme 2 (ACE2) …

Elucidating the neuropathologic mechanisms of SARS-CoV-2 infection

M Pacheco-Herrero, LO Soto-Rojas… - Frontiers in …, 2021 - frontiersin.org
The current pandemic caused by the new severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has become a public health emergency. To date, March 1, 2021, coronavirus …

Spike proteins of SARS-CoV-2 induce pathological changes in molecular delivery and metabolic function in the brain endothelial cells

ES Kim, MT Jeon, KS Kim, S Lee, S Kim, DG Kim - Viruses, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes the
coronavirus disease (COVID-19), is currently infecting millions of people worldwide and is …