[HTML][HTML] Evidence of endothelial dysfunction in the development of Alzheimer's disease: is Alzheimer'sa vascular disorder?

RJ Kelleher, RL Soiza - American journal of cardiovascular disease, 2013 - ncbi.nlm.nih.gov
The etiology of Alzheimer's disease (AD) remains unclear. The emerging view is that
cerebrovascular dysfunction is a feature not only of cerebrovascular diseases, such as …

Cerebrovascular and cardiovascular pathology in Alzheimer's disease

JC de la Torre - International Review of Neurobiology, 2009 - Elsevier
Presently, compelling evidence indicates that Alzheimer's disease (AD) is a vascular
disorder with neurodegenerative consequences and should be treated as such. A …

Does vascular pathology contribute to Alzheimer changes?

RN Kalaria, R Akinyemi, M Ihara - Journal of the neurological sciences, 2012 - Elsevier
In recent years there has been increased interest in whether vascular disease contributes to
Alzheimer's disease (AD). This review considers how modifiable risk factors such as …

The vascular contribution to Alzheimer's disease

R Altman, JC Rutledge - Clinical science, 2010 - portlandpress.com
AD (Alzheimer's disease) is a progressive neurodegenerative disease of unknown origin.
Despite questions as to the underlying cause (s) of this disease, shared risk factors for both …

Role of vascular risk factors and vascular dysfunction in Alzheimer's disease

DL Dickstein, J Walsh, H Brautigam… - Mount Sinai Journal …, 2010 - Wiley Online Library
Recent findings indicate that vascular risk factors and neurovascular dysfunction play
integral roles in the pathogenesis of Alzheimer's disease. In addition to aging, the most …

The overlap between neurodegenerative and vascular factors in the pathogenesis of dementia

C Iadecola - Acta neuropathologica, 2010 - Springer
There is increasing evidence that cerebrovascular dysfunction plays a role not only in
vascular causes of cognitive impairment but also in Alzheimer's disease (AD). Vascular risk …

Vascular abnormalities: The insidious pathogenesis of Alzheimer's disease☆

J Shi, G Perry, MA Smith, RP Friedland - Neurobiology of Aging, 2000 - Elsevier
Alzheimer's disease (AD) and cerebrovascular dementia (CVD) are two major causes of
senile dementia in elderly individuals. Mounting evidence from epidemiological, clinical, and …

[HTML][HTML] An integrated view on vascular dysfunction in Alzheimer's disease

J Klohs - Neurodegenerative Diseases, 2019 - karger.com
Background: Cerebrovascular disease is a common comorbidity in patients with Alzheimer's
disease (AD). It is believed to contribute additively to the cognitive impairment and to lower …

Vascular aspects in Alzheimer's disease

I Skoog - Advances in Dementia Research, 2000 - Springer
Alzheimer's disease is a primary degenerative dementia and is not considered to be of
vascular origin. Furthermore, severe cerebrovascular diseases are generally exclusionary …

Vascular dysfunction in Alzheimer's disease: a prelude to the pathological process or a consequence of it?

K Govindpani, LG McNamara, NR Smith… - Journal of clinical …, 2019 - mdpi.com
Alzheimer's disease (AD) is the most prevalent form of dementia. Despite decades of
research following several theoretical and clinical lines, all existing treatments for the …