Comparison the effects of hypoxia-mimicking agents on migration-related signaling pathways in mesenchymal stem cells

A Heirani-Tabasi, M Mirahmadi, MA Mishan… - Cell and Tissue …, 2020 - Springer
Adipose-derived mesenchymal stem cells (Ad-MSCs) have been designated as the
promising agents for clinical applications for easy accessibility, multi-linage differentiation …

In vitro migration capacity of human adipose tissue-derived mesenchymal stem cells reflects their expression of receptors for chemokines and growth factors

SJ Baek, SK Kang, JC Ra - Experimental & molecular medicine, 2011 - nature.com
The homing properties of adipose tissue-derived mesenchymal stem cells (AdMSCs) have
stimulated intravenous applications for their use in stem cell therapy. However, the soluble …

Hypoxia changes chemotaxis behaviour of mesenchymal stem cells via HIF‐1α signalling

W Xu, R Xu, Z Li, Y Wang, R Hu - Journal of cellular and …, 2019 - Wiley Online Library
Mesenchymal stem cells (MSCs) have drawn great attention because of their therapeutic
potential. It has been suggested that intra‐venous infused MSCs could migrate the site of …

Injectable hydrogel delivery plus preconditioning of mesenchymal stem cells: exploitation of SDF‐1/CXCR4 axis toward enhancing the efficacy of stem cells' homing

H Naderi‐Meshkin, MM Matin… - Cell biology …, 2016 - Wiley Online Library
Clinical applications of mesenchymal stem cells (MSCs) rely on their capacity to home and
engraft in the appropriate target injury tissues for the long term. However, their homing …

Dissection of the biphasic nature of hypoxia-induced motogenic action in bone marrow-derived human mesenchymal stem cells

C Busletta, E Novo, L Valfrè Di Bonzo, D Povero… - Stem …, 2011 - academic.oup.com
Hypoxic conditions have been reported to facilitate preservation of undifferentiated
mesenchymal stem cell (MSC) phenotype and positively affect their colony-forming potential …

Insight in Hypoxia‐Mimetic Agents as Potential Tools for Mesenchymal Stem Cell Priming in Regenerative Medicine

A Nowak-Stępniowska, PN Osuchowska… - Stem Cells …, 2022 - Wiley Online Library
Hypoxia‐mimetic agents are new potential tools in MSC priming instead of hypoxia
incubators or chambers. Several pharmaceutical/chemical hypoxia‐mimetic agents can be …

[HTML][HTML] Chemically primed bone-marrow derived mesenchymal stem cells show enhanced expression of chemokine receptors contributed to their migration capability

HR Bidkhori, N Ahmadiankia, MM Matin… - Iranian Journal of …, 2016 - ncbi.nlm.nih.gov
Objective (s): The limited homing potential of bone-marrow-derived mesenchymal stem cells
(BM-MSC) is the key obstacle in MSC-based therapy. It is believed that chemokines and …

Hypoxia-inducible factor-1α is essential for hypoxia-induced mesenchymal stem cell mobilization into the peripheral blood

L Liu, Q Yu, J Lin, X Lai, W Cao, K Du… - Stem cells and …, 2011 - liebertpub.com
Mobilization of mesenchymal stem cells (MSCs) is a promising strategy for tissue repair and
regenerative medicine. The establishment of an appropriate animal model and clarification …

Hypoxia and low‐dose inflammatory stimulus synergistically enhance bone marrow mesenchymal stem cell migration

Y Yu, Y Yin, RX Wu, XT He, XY Zhang… - Cell …, 2017 - Wiley Online Library
Objectives Cell migration is necessary for numerous physiological cell processes. Although
either inflammatory or hypoxic stimuli of certain dose and duration have positive influence …

LincRNA-p21 promotes mesenchymal stem cell migration capacity and survival through hypoxic preconditioning

SS Meng, XP Xu, W Chang, ZH Lu, LL Huang… - Stem cell research & …, 2018 - Springer
Abstract Background Mesenchymal stem cells (MSCs) derived from bone marrow have
potent stabilizing effects for the treatment of acute respiratory distress syndrome (ARDS) …