Human immunodeficiency virus (HIV) genetic diversity informs stage of HIV-1 infection among patients receiving antiretroviral therapy in Botswana
M Ragonnet-Cronin, T Golubchik… - The Journal of …, 2022 - academic.oup.com
Background Human immunodeficiency virus (HIV)-1 genetic diversity increases during
infection and can help infer the time elapsed since infection. However, the effect of …
infection and can help infer the time elapsed since infection. However, the effect of …
[PDF][PDF] HIV genetic diversity informs stage of HIV-1 infection among patients receiving antiretroviral therapy in Botswana
HIV genetic diversity informs stage of HIV-1 infection among patients receiving antiretroviral
therapy in Botswana Page 1 © The Author(s) 2021. Published by Oxford University Press for …
therapy in Botswana Page 1 © The Author(s) 2021. Published by Oxford University Press for …
Viral diversity based on next-generation sequencing of HIV-1 provides precise estimates of infection recency and time since infection
LA Carlisle, T Turk, K Kusejko… - The Journal of …, 2019 - academic.oup.com
Background Human immunodeficiency virus type 1 (HIV-1) genetic diversity increases over
the course of infection and can be used to infer the time since infection and, consequently …
the course of infection and can be used to infer the time since infection and, consequently …
Association between HIV genotype, viral load and disease progression in a cohort of Thai men who have sex with men with estimated dates of HIV infection
W Leelawiwat, S Pattanasin, A Sriporn, P Wasinrapee… - Plos one, 2018 - journals.plos.org
Background Differences between HIV genotypes may affect HIV disease progression. We
examined infecting HIV genotypes and their association with disease progression in a …
examined infecting HIV genotypes and their association with disease progression in a …
Estimating time of HIV-1 infection from next-generation sequence diversity
Estimating the time since infection (TI) in newly diagnosed HIV-1 patients is challenging, but
important to understand the epidemiology of the infection. Here we explore the utility of virus …
important to understand the epidemiology of the infection. Here we explore the utility of virus …
Genetic diversity from proviral DNA as a proxy for time since HIV-1 infection
M Zeeb, P Frischknecht, M Huber… - The Journal of …, 2024 - academic.oup.com
HIV-1 RNA genetic diversity predicts time since infection, which is important for clinical care
and research. It is unclear, however, whether proviral DNA genetic diversity sampled under …
and research. It is unclear, however, whether proviral DNA genetic diversity sampled under …
Pairwise diversity and tMRCA as potential markers for HIV infection recency
Intrahost human immunodeficiency virus (HIV)-1 diversity increases linearly over time. We
assessed the extent to which mean pairwise distances and the time to the most recent …
assessed the extent to which mean pairwise distances and the time to the most recent …
Clinical utility of HIV standard genotyping among antiretroviral-naive individuals with unknown duration of infection
D Smith, N Moini, R Pesano, E Cachay… - Clinical infectious …, 2007 - academic.oup.com
In clinical settings, we have found a high rate of human immunodeficiency virus (HIV) drug
resistance among antiretroviral-naive patients for whom the duration of infection was …
resistance among antiretroviral-naive patients for whom the duration of infection was …
Analysis of viral diversity in relation to the recency of HIV-1C infection in Botswana
Background Cross-sectional, biomarker methods to determine HIV infection recency present
a promising and cost-effective alternative to the repeated testing of uninfected individuals …
a promising and cost-effective alternative to the repeated testing of uninfected individuals …
Deep-sequencing of viral genomes from a large and diverse cohort of treatment-naive HIV-infected persons shows associations between intrahost genetic diversity …
M Gabrielaite, M Bennedbæk… - PLoS computational …, 2023 - journals.plos.org
Background Infection with human immunodeficiency virus type 1 (HIV) typically results from
transmission of a small and genetically uniform viral population. Following transmission, the …
transmission of a small and genetically uniform viral population. Following transmission, the …
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