Human immunodeficiency virus (HIV) genetic diversity informs stage of HIV-1 infection among patients receiving antiretroviral therapy in Botswana

M Ragonnet-Cronin, T Golubchik… - The Journal of …, 2022 - academic.oup.com
Background Human immunodeficiency virus (HIV)-1 genetic diversity increases during
infection and can help infer the time elapsed since infection. However, the effect of …

[PDF][PDF] HIV genetic diversity informs stage of HIV-1 infection among patients receiving antiretroviral therapy in Botswana

M Ragonnet-Cronin, T Golubchik, S Moyo, C Fraser… - J Infect Dis, 2021 - scholar.archive.org
HIV genetic diversity informs stage of HIV-1 infection among patients receiving antiretroviral
therapy in Botswana Page 1 © The Author(s) 2021. Published by Oxford University Press for …

Viral diversity based on next-generation sequencing of HIV-1 provides precise estimates of infection recency and time since infection

LA Carlisle, T Turk, K Kusejko… - The Journal of …, 2019 - academic.oup.com
Background Human immunodeficiency virus type 1 (HIV-1) genetic diversity increases over
the course of infection and can be used to infer the time since infection and, consequently …

Association between HIV genotype, viral load and disease progression in a cohort of Thai men who have sex with men with estimated dates of HIV infection

W Leelawiwat, S Pattanasin, A Sriporn, P Wasinrapee… - Plos one, 2018 - journals.plos.org
Background Differences between HIV genotypes may affect HIV disease progression. We
examined infecting HIV genotypes and their association with disease progression in a …

Estimating time of HIV-1 infection from next-generation sequence diversity

V Puller, R Neher, J Albert - PLoS Computational Biology, 2017 - journals.plos.org
Estimating the time since infection (TI) in newly diagnosed HIV-1 patients is challenging, but
important to understand the epidemiology of the infection. Here we explore the utility of virus …

Genetic diversity from proviral DNA as a proxy for time since HIV-1 infection

M Zeeb, P Frischknecht, M Huber… - The Journal of …, 2024 - academic.oup.com
HIV-1 RNA genetic diversity predicts time since infection, which is important for clinical care
and research. It is unclear, however, whether proviral DNA genetic diversity sampled under …

Pairwise diversity and tMRCA as potential markers for HIV infection recency

S Moyo, E Wilkinson, A Vandormael, R Wang, J Weng… - Medicine, 2017 - journals.lww.com
Intrahost human immunodeficiency virus (HIV)-1 diversity increases linearly over time. We
assessed the extent to which mean pairwise distances and the time to the most recent …

Clinical utility of HIV standard genotyping among antiretroviral-naive individuals with unknown duration of infection

D Smith, N Moini, R Pesano, E Cachay… - Clinical infectious …, 2007 - academic.oup.com
In clinical settings, we have found a high rate of human immunodeficiency virus (HIV) drug
resistance among antiretroviral-naive patients for whom the duration of infection was …

Analysis of viral diversity in relation to the recency of HIV-1C infection in Botswana

S Moyo, A Vandormael, E Wilkinson, S Engelbrecht… - PLoS …, 2016 - journals.plos.org
Background Cross-sectional, biomarker methods to determine HIV infection recency present
a promising and cost-effective alternative to the repeated testing of uninfected individuals …

Deep-sequencing of viral genomes from a large and diverse cohort of treatment-naive HIV-infected persons shows associations between intrahost genetic diversity …

M Gabrielaite, M Bennedbæk… - PLoS computational …, 2023 - journals.plos.org
Background Infection with human immunodeficiency virus type 1 (HIV) typically results from
transmission of a small and genetically uniform viral population. Following transmission, the …