Proinflammatory properties of coplanar PCBs: in vitro and in vivo evidence

B Hennig, P Meerarani, R Slim, M Toborek… - Toxicology and applied …, 2002 - Elsevier
So-called coplanar polychlorinated biphenyls (PCBs), as well as other environmental
contaminants that are aryl hydrocarbon receptor (AhR) agonists, may compromise the …

PCB 104-induced proinflammatory reactions in human vascular endothelial cells: relationship to cancer metastasis and atherogenesis

W Choi, SY Eum, YW Lee, B Hennig… - Toxicological …, 2003 - academic.oup.com
Polychlorinated biphenyls (PCBs) are widespread environmental contaminants that are
known to induce carcinogenic and possibly atherogenic events. Recent evidence suggests …

Omega-3 fatty acid oxidation products prevent vascular endothelial cell activation by coplanar polychlorinated biphenyls

Z Majkova, J Layne, M Sunkara, AJ Morris… - Toxicology and applied …, 2011 - Elsevier
Coplanar polychlorinated biphenyls (PCBs) may facilitate development of atherosclerosis by
stimulating pro-inflammatory pathways in the vascular endothelium. Nutrition, including fish …

Dietary flavonoids modulate PCB-induced oxidative stress, CYP1A1 induction, and AhR-DNA binding activity in vascular endothelial cells

P Ramadass, P Meerarani, M Toborek… - Toxicological …, 2003 - academic.oup.com
Polychlorinated biphenyls (PCBs), especially the more coplanar PCBs, have been shown to
induce oxidative stress, various transcription factors, and subsequent inflammatory …

Cellular glutathione status modulates polychlorinated biphenyl-induced stress response and apoptosis in vascular endothelial cells

R Slim, M Toborek, LW Robertson, HJ Lehmler… - Toxicology and applied …, 2000 - Elsevier
Exposure to environmental contaminants, such as polychlorinated biphenyls (PCBs), may
severely compromise normal function of vascular endothelial cells (EC). We have previously …

Exposure to polychlorinated biphenyls causes endothelial cell dysfunction

M Toborek, SW Barger, MP Mattson… - Journal of …, 1995 - Wiley Online Library
Environmental chemicals, such as polychlorinated biphenyls (PCBs), may be atherogenic by
disrupting normal functions of the vascular endothelium. To investigate this hypothesis …

Polychlorinated biphenyls and links to cardiovascular disease

JT Perkins, MC Petriello, BJ Newsome… - … Science and Pollution …, 2016 - Springer
The pathology of cardiovascular disease is multi-faceted, with links to many modifiable and
non-modifiable risk factors. Epidemiological evidence now implicates exposure to persistent …

PCB-induced oxidative stress in endothelial cells: modulation by nutrients

B Hennig, BD Hammock, R Slim, M Toborek… - International journal of …, 2002 - Elsevier
There is an increasing body of evidence suggesting that exposure to Superfund chemicals
may have adverse consequences on many organ systems, as well as carcinogenic and …

PCB 126 induces monocyte/macrophage polarization and inflammation through AhR and NF-κB pathways

C Wang, MC Petriello, B Zhu, B Hennig - Toxicology and applied …, 2019 - Elsevier
Polychlorinated biphenyls (PCBs) are persistent organic pollutants that contribute to
inflammatory diseases such as atherosclerosis, and macrophages play a key role in the …

Antioxidant protection against PCB-mediated endothelial cell activation.

R Slim, M Toborek, LW Robertson… - … sciences: an official …, 1999 - academic.oup.com
Certain environmental contaminants such as polyhalogenated aromatic hydrocarbons may
be implicated in diseases of the vasculature by compromising normal functions of vascular …