Interactions between the enteric nervous system (ENS) and intestinal epithelium are thought
to play a vital role in intestinal homeostasis. How the ENS monitors the frontier with …

Background The intestinal microbiota plays an important role in regulating gastrointestinal
(GI) physiology in part through interactions with the enteric nervous system (ENS) …

Enteroendocrine cells are specialized sensory cells of the gut-brain axis that are sparsely
distributed along the intestinal epithelium. The functions of enteroendocrine cells have …

The microbiota-gut-brain axis transmits bidirectional communication between the gut and
the central nervous system and links the emotional and cognitive centers of the brain with …

The gastrointestinal tract harbors an intrinsic neuronal network, the enteric nervous system
(ENS). The ENS controls motility, fluid homeostasis, and blood flow, but also interacts with …

Gut bacteria play an important role in the digestion of food, immune activation, and
regulation of entero-endocrine signaling pathways, but also communicate with the central …

Highlights•Microbe-derived molecules influence disease outcomes through diverse
mechanisms.•Short-chain fatty acid (SCFA) production in the gut can alter microglial …

Trillions of bacteria reside within our gastrointestinal tract, ideally forming a mutually
beneficial relationship between us. However, persistent changes in diet and lifestyle in the …

Background and aims As the importance of gut–brain interactions increases, understanding
how specific gut microbes interact with the enteric nervous system (ENS), which is the first …

The enteric nervous system is largely autonomous, and the central nervous system is
compartmentalized behind the blood-brain barrier. Yet the intestinal microbiota shapes gut …